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NPC1 ELISA Kits

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

5 results:

NPC1 ELISA Kit (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate
Catalog No. ABIN6958195
$810.53
Plus shipping costs $45.00
96 tests
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

NPC1 ELISA Kit (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Human Colorimetric Sandwich ELISA Cell Culture Supernatant, Cell Samples, Plasma, Serum, Tissue Lysate
Catalog No. ABIN6951470
$501.60
Plus shipping costs $45.00
96 tests
local_shipping Shipping to: United States
Delivery in 21 to 31 Business Days

NPC1 ELISA Kit (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Chicken Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
Catalog No. ABIN1056422
$707.14
Plus shipping costs $45.00
96 tests
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

NPC1 ELISA Kit (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Monkey Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
Catalog No. ABIN1056423
$707.14
Plus shipping costs $45.00
96 tests
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

NPC1 ELISA Kit (Niemann-Pick Disease, Type C1) ELISA Kit

Synonym: NPC intracellular cholesterol transporter 1 NPC1 Reactivity: Sheep Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
Catalog No. ABIN1056424
$707.14
Plus shipping costs $45.00
96 tests
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days
  • Type Kit
    • Kit
  • Target Niemann-Pick Disease, Type C1 (NPC1)
    • Niemann-Pick Disease, Type C1 (NPC1)
    • Interferon gamma (IFNG)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Interleukin 10 (IL10)
    • Interleukin 4 (IL4)
    • Tumor Necrosis Factor alpha (TNF)
    • Interleukin 6 (IL6)
    • Tumor Protein P53 (TP53)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Transforming Growth Factor, beta 1 (TGFB1)
    • IgG
    • Albumin (ALB)
    • Leptin (LEP)
    • Follicle-Stimulating Hormone (FSH)
    • Interleukin 8 (IL8)
    • Jun Proto-Oncogene (JUN)
    • IgA
    • Interleukin 1 alpha (IL1A)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Interleukin 13 (IL13)
    • Interleukin 17A (IL17A)
    • Insulin (INS)
    • Interleukin 12 (IL12)
    • Adiponectin (ADIPOQ)
    • Chemokine (C-C Motif) Ligand 5 (CCL5)
    • Interleukin 5 (IL5)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Metalloproteinase Inhibitor 2 (TIMP2)
    • Cystatin C (CST3)
    • Platelet-Derived Growth Factor beta Polypeptide (PDGFB)
    • Annexin A5 (ANXA5)
    • Cortisol
    • Retinol Binding Protein 4, Plasma (RBP4)
    • Interleukin 1 Receptor Antagonist (IL1RN)
    • Luteinizing Hormone (LH)
    • Prolactin (PRL)
    • Resistin (RETN)
    • Complement Component 3 (C3)
    • Fas Ligand (TNF Superfamily, Member 6) (FASL)
    • Insulin-Like Growth Factor 2 (IGF2)
    • Thyroxine T4 (T4)
    • Epidermal Growth Factor (EGF)
    • Erythropoietin (EPO)
    • IgM
    • Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9)
    • Mitogen-Activated Protein Kinase 14 (MAPK14)
    • Nuclear Factor-KB P65 (NFkBP65)
    • Transforming Growth Factor, beta 2 (TGFB2)
    • Angiopoietin 1 (ANGPT1)
  • Application
    • ELISA
  • Reactivity
    • Human
    • Chicken
    • Monkey
    • Sheep
  • Images available
  • Method Type
    • Sandwich ELISA
  • Analytical Method
    • Quantitative
  • Detection Method
    • Colorimetric
  • Plate
    • Pre-coated
  • Sample
    • Cell Culture Supernatant
    • Plasma
    • Serum
    • Tissue Homogenate
    • Cell Lysate
    • Cell Samples
    • Tissue Lysate

NPC1 Antigen Profile

Protein Summary

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) antibody
  • Niemann-Pick disease, type C1 (npc1) antibody
  • Niemann-Pick C1 protein (LOC579887) antibody
  • NPC intracellular cholesterol transporter 1 (Npc1) antibody
  • A430089E03Rik antibody
  • C85354 antibody
  • Cdig2 antibody
  • D18Ertd139e antibody
  • D18Ertd723e antibody
  • im:7149020 antibody
  • lcsd antibody
  • nmf164 antibody
  • NPC antibody
  • spm antibody
  • wu:fb53a12 antibody
  • wu:fc29a12 antibody

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus

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