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anti-NSMCE2 Antibodies

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination.

30 results:

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (AA 1-247) Primary Antibody

NSMCE2 Reactivity: Human IF, WB Host: Mouse Polyclonal unconjugated
Pubmed 2
Catalog No. ABIN531598
$440.00
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (C-Term) Primary Antibody

NSMCE2 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1030522
$380.00
Plus shipping costs $45.00
0.1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (N-Term) Primary Antibody

NSMCE2 Reactivity: Human ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3185961
$396.83
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (C-Term) Primary Antibody

NSMCE2 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6657203
$379.00
Plus shipping costs $45.00 and $24.00 dry ice
100 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (Middle Region) Primary Antibody

NSMCE2 Reactivity: Human, Mouse, Cow, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786320
$389.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (C-Term) Primary Antibody

NSMCE2 Reactivity: Human, Mouse, Rat EIA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783606
$511.50
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (AA 107-156) Primary Antibody

NSMCE2 Reactivity: Human, Cow, Horse, Pig, Rabbit IHC, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6755380
$727.83
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 14 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) (AA 30-110) Primary Antibody

NSMCE2 Reactivity: Human ELISA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6287675
$318.71
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) Primary Antibody

NSMCE2 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6388802
$367.82
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-NSMCE2 antibody (Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) Primary Antibody

NSMCE2 Reactivity: Human FACS, IF, WB Host: Mouse Monoclonal 4A2 unconjugated
Catalog No. ABIN2147832
$990.18
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
  • Type Primary
    • Primary
  • Target Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
    • Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Tumor Necrosis Factor alpha (TNF)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • Albumin (ALB)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Myc Proto-Oncogene protein (MYC)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Integrin alpha M (ITGAM)
    • CD44
    • CD8
    • Histone H4
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Jun Proto-Oncogene (JUN)
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD5 Molecule (CD5)
    • Interleukin 2 (IL2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Synuclein, alpha (SNCA)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Androgen Receptor (AR)
    • CD14
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD34
    • Cyclin-Dependent Kinase 1 (CDK1)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Flow Cytometry (FACS)
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunoprecipitation (IP)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Rabbit
    • Horse
    • Cow
    • Guinea Pig
    • Chicken
    • Pig
  • Cited in publications
  • Images available
  • Host
    • Rabbit
    • Mouse
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 4A2
    • 6A6
  • Binding Specificity
    • AA 1-247
    • C-Term
    • N-Term
    • AA 1-50
    • AA 107-156
    • AA 125-175
    • AA 197-247
    • AA 227-242
    • AA 30-110
    • Middle Region
  • Conjugate
    • Un-conjugated
    • Biotin
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • FITC
    • HRP
  • Isotype
    • IgG
    • IgG1
    • IgG2a
  • Format
    • Liquid
    • Lyophilized

NSMCE2 Antigen Profile

Protein Summary

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).

Gene names and symbols associated with NSMCE2

  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2) antibody
  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2) antibody
  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L) antibody
  • Smc5-6 complex non-SMC subunit 2 (nse2) antibody
  • 1110014D18Rik antibody
  • AI661537 antibody
  • C8orf36 antibody
  • MMS21 antibody
  • Non-SMC element 2 antibody
  • NSE2 antibody
  • RGD1305156 antibody
  • ZMIZ7 antibody

Protein level used designations for NSMCE2

E3 SUMO-protein ligase NSE2 , MMS21 homolog , non-structural maintenance of chromosomes element 2 homolog , non-SMC element 2 homolog , hMMS21 , methyl methanesulfonate sensitivity gene 21 , zinc finger, MIZ-type containing 7 , non-SMC element 2 homolog (MMS21, S. cerevisiae) , Non-structural maintenance of chromosomes element 2

GENE ID SPECIES
68501 Mus musculus
299957 Rattus norvegicus
286053 Homo sapiens
519974 Bos taurus
379272 Xenopus laevis
100724833 Cavia porcellus
2542312 Schizosaccharomyces pombe 972h-

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