anti-Nuclear Factor, Interleukin 3 Regulated (NFIL3) Antibodies

Expression of interleukin-3 (IL3\; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Additionally we are shipping NFIL3 Kits (33) and NFIL3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFIL3 4783 Q16649
NFIL3 114519 Q6IMZ0
NFIL3 18030 O08750
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Top anti-NFIL3 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Mouse Target Name: NFIL3 Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml WB Suggested Anti-NFIL3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human brain 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, FACS, WB ABIN184644 staining (0.5µg/ml) of HepG2 lysate (RIPA buffer, 20µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN184644 staining (1µg/ml) of Jurkat nuclear cell lysate (RIPA buffer, 20µg total protein per lane). Detected using chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-NFIL3 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T Rabbit Anti-NFIL3 Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated IC, IF, WB Western blot analysis of NFIL3 expression in HeLa (A), K562 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293/K562 cells, using NFIL3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in MCF-7 cell line lysates (35ug/lane) using NFIL3  Antibody (N-term). This demonstrates this antibody detected the NFIL3 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Goat Un-conjugated WB 100 μg 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Available
$363.46
Details

Top referenced anti-NFIL3 Antibodies

  1. Human Polyclonal NFIL3 Primary Antibody for ELISA, WB - ABIN257663 : Zhang, Zhang, Kornuc, Kwan, Frank, Nimer: Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter. in Molecular and cellular biology 1995 (PubMed)

More Antibodies against NFIL3 Interaction Partners

Human Nuclear Factor, Interleukin 3 Regulated (NFIL3) interaction partners

  1. E4BP4 contribute to enhance the GCs sensitivity.

  2. STAT3/NFIL3 axis-inhibited apoptosis is a novel mechanism of chemotherapy resistance in choriocarcinoma. With the suppression of STAT3/NFIL3 axis and apoptosis induction, RA is a potential agent or lead candidate for improving chemotherapy.

  3. Our results indicate that the action of E4bp4 in NK cells is highly regulated and can potentially be strongly influenced by extrinsic stimuli

  4. data provide evidence that E4BP4 attenuates RASSF8-mediated anti-proliferation and apoptosis, shedding mechanistic insights into RASSF8 down-regulation in breast cancers.

  5. Here we review the regulatory mechanisms of E4BP4 engaging in not only the biological function but also the development of immune-mediated diseases, paving the way for future therapies

  6. glucocorticoid-mediated transactivating pathway may support eosinophil viability in IL-5-stimulated cells through synergistic upregulation of NFIL3

  7. E4BP4 and BIM regulation correlated with that of RCAN1-1. A putative GRE and four EBPREs were identified within 1500bp upstream from the transcription start site of RCAN1-1

  8. Results conclude that the transcriptional repressor E4BP4 plays a role in repressing epigenetically regulated SOSTDC1 expression in breast cancer cells, which can be reverted by E4BP4 silencing.

  9. NFIL3 plays a neuroprotective role in neurons and constitutes a potential therapeutic target for neurodegeneration.

  10. Data indicate that E4BP4 can inhibit CD40L expression through epigenetic modifications in the promoter region of CD40L.

  11. NFIL3 alters cancer cell behavior and FOXO function by acting on chromatin to restrict the menu of FOXO target genes

  12. The clock-regulated and immune system modulator transcription factor E4BP4/ NFIL3 likely regulates the expression of both appb in zebrafish and APP in humans.

  13. G9a mediates E4BP4-dependent suppression of hepatic Fgf21 by enhancing histone methylation (H3K9me2) of the Fgf21 promoter

  14. Conclude that E4BP4 plays as a survival factor in heart and E4BP4 is essential for proper embryonic heart development.

  15. This report demonstrates that GC-mediated upregulation of the bZIP transcriptional repressor gene, E4BP4, is dependent on [Ca2+]i levels, and correlates with GC-evoked apoptosis of GC-sensitive CEM-C7-14 cells.

  16. E4BP4 has a role as osteoblast transcriptional repressor in inhibiting both Runx2 and Osterix in myeloma bone disease

  17. Identification of adjacent binding sites for the YY1 and E4BP4 transcription factors in the PrP (Prion) gene promoter.

Zebrafish Nuclear Factor, Interleukin 3 Regulated (NFIL3) interaction partners

  1. Study shows that Nfil3 is enriched in the myeloid compartment of adult zebrafish including eosinophils.

  2. conclude that E4BP4/NIFL3 plays as a survival factor in heart and E4BP4 is essential for proper embryonic heart development.

Mouse (Murine) Nuclear Factor, Interleukin 3 Regulated (NFIL3) interaction partners

  1. Our results indicate that the action of E4bp4 in NK cells is highly regulated and can potentially be strongly influenced by extrinsic stimuli

  2. Data indicate E4BP4/NFIL3 as a direct Smad3 target gene critical for NK cell differentiation.

  3. These findings provide mechanistic insight into how the intestinal microbiota regulates body composition and establish NFIL3 as an essential molecular link among the microbiota, the circadian clock, and host metabolism.

  4. E4BP4 acts as a key pro-adipogenic transcription factor by trans-repressing COX2 in glucocorticoid-associated adipocyte differentiation.

  5. NFIL3 functions as an important regulator of glucose homeostasis in the liver by limiting CREB-mediated hepatic gluconeogenesis.

  6. We identified PD-1 to be specifically expressed in PLZF(+) ILCp and revealed that the timing and order of expression of the transcription factors NFIL3, ID2, and TCF-1 was critical. Importantly, induction of ILC lineage commitment required only transient expression of NFIL3 prior to ID2 and TCF-1 expression.

  7. Uterine lumen closure, early embryonic development, and differentiation of antimesometrial decidua were delayed in Nfil3(-/-) implantation sites. Major disturbances to the decidual-trophoblast interface that did not lead to fetal death were attributed to NFIL3 deficiency in trophoblast.

  8. In hepatocytes, E4BP4 interacts with nuclear SREBP-1c to preserve its acetylation, and subsequently protects it from ubiquitination-dependent degradation

  9. study found that approximately one quarter of the submandibular salivary gland (SMG) NK cells develop independently of NFIL3; data show that the SMG tissue environment shapes a unique repertoire of NK-like cells with distinct phenotypes

  10. New direct Wnt/beta-catenin target gene Nfil3 , which induced epithelial-mesenchymal transition, cell migration and experimental metastasis of Colorectal cancer cells was identified.

  11. removal of NFIL3 in vivo does not recapitulate the regeneration-promoting effects that were previously observed in vitro.

  12. These findings establish that NFIL3 directs the differentiation of a committed innate lymphoid cell precursor.

  13. These data identify an IL-27/NFIL3 signalling axis as a key regulator of effector T-cell responses via induction of Tim-3, IL-10 and T-cell dysfunction.

  14. establish NFIL3 as a key regulator of common helper-like innate lymphoid cells progenitors as they emerge during early lymphopoiesis

  15. Iso-mediated induction of Nfil3 in osteoblasts regulates the expression of Ptgs2 by driving the expression of circadian clock genes

  16. E4BP4 plays a crucial role in glucocorticoid -evoked apoptosis of osteoblasts by enabling induction of Bim

  17. Nfil3 is a key regulator of the development of innate lymphoid cell subsets essential for immune protection in the lung and gut.

  18. Nfil3 is critical for normal development of gut-associated type 3 innate lymphoid cells. Nfil3 deficiency severely compromises intestinal innate immune defense against acute bacterial infection with Citrobacter rodentium and Clostridium difficile.

  19. signals transmitted by Ly49H and proinflammatory cytokines are sufficient to promote NK cell differentiation in the absence of Nfil3.

  20. E4bp4 is required for commitment to the natural killer (NK) lineage and promotes NK development by directly regulating the expression of the downstream transcription factors Eomes and Id2.

NFIL3 Antigen Profile

Protein Summary

Expression of interleukin-3 (IL3\; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995

Gene names and symbols associated with NFIL3

  • nuclear factor, interleukin 3 regulated (nfil3) antibody
  • nuclear factor, interleukin 3 regulated (NFIL3) antibody
  • nuclear factor, interleukin 3 regulated (Nfil3) antibody
  • nuclear factor, interleukin 3 regulated L homeolog (nfil3.L) antibody
  • nuclear factor, interleukin 3, regulated (Nfil3) antibody
  • AV225605 antibody
  • E4BP4 antibody
  • E4BP4-1 antibody
  • IL3BP1 antibody
  • MGC107826 antibody
  • NF-IL3A antibody
  • NFIL3 antibody
  • NFIL3A antibody
  • zgc:100867 antibody

Protein level used designations for NFIL3

nuclear factor, interleukin 3 regulated , nuclear factor interleukin-3-regulated protein-like , E4 promoter-binding protein 4 , interleukin-3 promoter transcriptional activator , interleukin-3-binding protein 1 , nuclear factor interleukin 3 regulated protein , nuclear factor interleukin-3-regulated protein , transcriptional activator NF-IL3A , E4 promoter binding-protein 4 , E4 binding protein 4-1 , E4BP4 , ze4bp4-1 , bZIP protein E4BP4 , cE4BP4 protein , embryo implantation-related NFIL3/E4BP4-like transcription factor

GENE ID SPECIES
548427 Xenopus (Silurana) tropicalis
704757 Macaca mulatta
100395886 Callithrix jacchus
100440595 Pongo abelii
742792 Pan troglodytes
100554409 Anolis carolinensis
100587135 Nomascus leucogenys
4783 Homo sapiens
476347 Canis lupus familiaris
506097 Bos taurus
114519 Rattus norvegicus
445509 Danio rerio
447503 Xenopus laevis
395326 Gallus gallus
100726742 Cavia porcellus
100153822 Sus scrofa
100217409 Ovis aries
18030 Mus musculus
100345297 Oryctolagus cuniculus
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