NFIL3 antibody (Nuclear Factor, Interleukin 3 Regulated) (Middle Region)

Details for Product anti-NFIL3 Antibody No. ABIN2777219
Antigen
  • e4bp4
  • il3bp1
  • nfil3a
  • nf-il3a
  • MGC107826
  • NFIL3
  • E4BP4
  • IL3BP1
  • NF-IL3A
  • NFIL3A
  • E4BP4-1
  • zgc:100867
  • AV225605
  • nuclear factor, interleukin 3 regulated
  • nuclear factor, interleukin 3 regulated L homeolog
  • nuclear factor, interleukin 3, regulated
  • nfil3
  • NFIL3
  • Nfil3
  • nfil3.L
Epitope
Middle Region
11
9
8
6
4
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish (Danio rerio)
84
45
40
6
5
4
3
3
2
1
1
1
1
Host
Rabbit
75
8
1
Clonality
Polyclonal
Conjugate
This NFIL3 antibody is un-conjugated
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
63
38
13
12
5
3
3
2
2
1
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human NFIL3
Blocking Peptide Blocking peptide for this product available: ABIN980664
Sequence GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
Characteristics This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others NFIL3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name NFIL3 (NFIL3 Antibody Abstract)
Background NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
Protein Size: 462
Molecular Weight 51 kDa
Gene ID 4783
NCBI Accession NM_005384, NP_005375
UniProt Q16649
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 462 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Nuclear Factor, Interleukin 3 Regulated (NFIL3) (Middle Region) antibody (ABIN2777219) Host: Mouse Target Name: NFIL3 Sample Tissue: Mouse Heart Antibody Dilution: 1ug/ml
Image no. 2 for anti-Nuclear Factor, Interleukin 3 Regulated (NFIL3) (Middle Region) antibody (ABIN2777219) WB Suggested Anti-NFIL3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positiv...
Background publications Priceman, Kirzner, Nary, Morris, Shankar, Sakamoto, Medh: "Calcium-dependent upregulation of E4BP4 expression correlates with glucocorticoid-evoked apoptosis of human leukemic CEM cells." in: Biochemical and biophysical research communications, Vol. 344, Issue 2, pp. 491-9, 2006 (PubMed).

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