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anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) Antibodies

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. Additionally we are shipping Nuclear Transcription Factor, X-Box Binding 1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFX1 4799 Q12986
NFX1 74164 B1AY10
NFX1 313166  
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Top anti-Nuclear Transcription Factor, X-Box Binding 1 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NFX1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate NFX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-NFX1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate Immunohistochemistry with Human Testis lysate tissue 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, ELISA, WB NFX1 monoclonal antibody (M01), clone 1D12 Western Blot analysis of NFX1 expression in Hela S3 NE . Immunofluorescence of monoclonal antibody to NFX1 on HeLa cell. [antibody concentration 30 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IP, WB Western Blot: NFX1 Antibody [NBP1-49933] - Detection of Human and Mouse NFX1 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg) and mouse NIH3T3 (M; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-NFX1 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate. NFX1 was also immunoprecipitated by rabbit anti-NFX1 antibodies which recognize upstream epitopes. For blotting immunoprecipitated NFX1 was used. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 11 to 13 Days
$335.04
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated IP, WB Western Blot: NFX1 Antibody [NBP1-49931] - Detection of Human NFX1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-NFX1 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. NFX1 was also immunoprecipitated by rabbit anti-NFX1 antibodies, which recognize downstream epitopes. For blotting immunoprecipitated NFX1 was used. Detection: Chemiluminescence with exposure times of 3 minutes (A and B). 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated IP Immunoprecipitation: NFX1 Antibody [NBP1-49932] - Detection of Human NFX1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-NFX1 antibody used for IP at 3 mcg/mg lysate. NFX1 was also immunoprecipitated by rabbit anti-NFX1 antibodies which recognize other epitopes. For blotting immunoprecipitated NFX1 was used at 0.4 mcg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds. 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

More Antibodies against Nuclear Transcription Factor, X-Box Binding 1 Interaction Partners

Human Nuclear Transcription Factor, X-Box Binding 1 (NFX1) interaction partners

  1. This study identifies NFX1-123 as a critical host protein partner through which 16E6 is able to subvert the immune response and in turn permit a long-lived high-risk Human papillomavirus infection.

  2. The results showed that a repressor complex composed of NFX1-91, mSin3A and histone deacetylase 1 was involved in the PKC-delta-induced repression of the hTERT promoter, which resulted in the repression of hTERT transcription.

  3. Human papillomavirus 16 E6 (16E6) interacts with the cellular protein NFX1-123, and they collaboratively increase the growth and differentiation master regulator, Notch1.

  4. NFX1-123 and human papillomavirus 16E6 upregulated Notch 1 expression in keratinocytes.

  5. a mechanism for HPV16 E6 activation of the NFkappaB pathway through NFX1-91

  6. HuD acts as a novel adaptor protein to recruit TAP for efficient export of ARE-containing mRNAs in neuronal cells

  7. the induction of hTERT telomerase by the HPV-16 E6/E6-AP complex involves targeting of NFX1-91, a newly identified repressor of telomerase, for ubiquitination and degradation.

  8. Nrf1 is normally targeted to the endoplasmic reticulum membrane and endoplasmic reticulum stress may play a role in modulating Nrf1 function as a transcriptional activator

  9. data suggest that NFX1-123 is integral to hTERT regulation in HPV16 E6-expressing epithelial cells and that the interaction between NFX1-123 and poly(A) binding proteins is critical to hTERT activity

  10. These data demonstrate that targeted degradation of NFX1-91 by E6/E6AP dissociates the mSin3A/HDAC complex from the hTERT promoter and induces hTERT transcription.

  11. NFX1-123 is a cytoplasmic protein that colocalizes with poly(A) binding proteins, and binds hTERT mRNA in HPV16 E6-expressing keratinocytes.

Mouse (Murine) Nuclear Transcription Factor, X-Box Binding 1 (NFX1) interaction partners

  1. Mutation E610G, quantitatively accounts for the Nxf1 modifier gene activity toward IAP insertion.

  2. nuclear accumulation and modulation of unfolded protein response regulated by subunit of phosphoinositide 3-kinase

  3. nuclear translocation regulated by p85alpha and p85beta monomers of PI3K

Nuclear Transcription Factor, X-Box Binding 1 (NFX1) Antigen Profile

Protein Summary

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Gene names and symbols associated with NFX1

  • nuclear transcription factor, X-box binding 1 (NFX1) antibody
  • nuclear transcription factor, x-box binding 1 (CpipJ_CPIJ011986) antibody
  • nuclear transcription factor, X-box binding 1 (nfx1) antibody
  • nuclear transcription factor, X-box binding 1 (Nfx1) antibody
  • 1300017N15Rik antibody
  • 3000003M19Rik antibody
  • NFX.1 antibody
  • NFX1 antibody
  • NFX2 antibody
  • TEG-42 antibody
  • Tex42 antibody

Protein level used designations for NFX1

nuclear transcription factor, X-box binding 1 , nuclear transcription factor, x-box binding 1 , transcriptional repressor NF-X1-like , nuclear transcription factor, X box-binding protein 1 , transcriptional repressor NF-X1 , m-Nfx.1 , nuclear X box binding factor 1 , testis expressed gene 42

GENE ID SPECIES
420796 Gallus gallus
465042 Pan troglodytes
6044908 Culex quinquefasciatus
100009971 Monodelphis domestica
100399247 Callithrix jacchus
100488254 Xenopus (Silurana) tropicalis
100590740 Nomascus leucogenys
4799 Homo sapiens
481581 Canis lupus familiaris
515680 Bos taurus
74164 Mus musculus
313166 Rattus norvegicus
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