Nucleolar and Spindle Associated Protein 1 Proteins (NUSAP1)

NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003 [PubMed 12963707]).[supplied by OMIM, Jun 2009].. Additionally we are shipping NUSAP1 Antibodies (71) and NUSAP1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NUSAP1 51203 Q9BXS6
NUSAP1 108907 Q9ERH4
Rat NUSAP1 NUSAP1 311336  
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Top NUSAP1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Yeast Zebrafish His tag   1 mg 60 to 71 Days
$3,250.50
Details
Yeast Cow His tag   1 mg 60 to 71 Days
$3,309.17
Details
Yeast Xenopus laevis His tag   1 mg 60 to 71 Days
$3,406.33
Details
Yeast Xenopus tropicalis His tag   1 mg 60 to 71 Days
$3,417.33
Details
Escherichia coli (E. coli) Human His tag   100 μg 15 to 18 Days
$560.00
Details
Escherichia coli (E. coli) Human Un-conjugated   100 μg 11 to 18 Days
$596.97
Details

NUSAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Nucleolar and Spindle Associated Protein 1 (NUSAP1) Interaction Partners

Human Nucleolar and Spindle Associated Protein 1 (NUSAP1) interaction partners

  1. Our results demonstrate thatNUSAP1 upregulation contributes to metastasis of cervical cancer by promoting CSC properties and EMT via Wnt/beta-catenin signaling and XAV-939 might serve as a potential tailored therapeutic option for patients with NUSAP1-ovexpressed cervical cancer.

  2. NUSAP1 silencing by siRNA inhibited colorectal cancer cell proliferation, and induces cell apoptosis. Moreover, NUSAP1 knockdown suppressed cell migration, cell invasion, and epithelial-to-mesenchymal transition.

  3. Study provides evidence that downregulation of NUSAP1 can inhibit the proliferation, migration, and invasion of IBC cells by regulating CDK1 and DLGAP5 expression and enhances the drug susceptibility to E-ADM.

  4. Study provides new insights and evidence that Nucleolar and spindle-associated protein (NUSAP1) over-expression was significantly correlated with progression and prognosis of glioblastoma multiforme. Furthermore, knockdown of NUSAP1 revealed its regulation on G2/M progression and cell proliferation (both in vitro and in vivo).

  5. Study suggests that NUSAP1 might be involved in glioma progression and can serve as a prognosis biomarker for glioma patients. NUSAP1 silencing suppresses malignant phenotypes of glioma cells, which offer a theoretical foundation for further investigation of NUSAP1 as a possible target with advantages for glioma treatment.

  6. NUSAP1 is overexpressed in colon cancer and high expression of NUSAP1 acts as an independent predictive factor for poor prognosis in colon cancer

  7. Findings indicated that NUSAP1 played an important role in promoting aggressiveness in astrocytoma via activating the HH pathway.

  8. our work provides a better understanding of the function of NUSAP1 in aggressive prostate cancers, provides rationale for using NUSAP1 as a prognostic biomarker, and sets the stage for developing improved therapeutic strategies for prostate and other cancers.

  9. NUSAP1 contributes to accurate chromosome segregation by acting as a co-factor for RanBP2-RanGAP1-UBC9 during cell division.

  10. Our results reveal an underlying mechanism by which NuSAP controls kinetochore microtubule dynamics spatially and temporally by modulating the depolymerisation function of MCAK in an Aurora B kinase-dependent manner.

  11. NuSAP governs chromosome oscillation via regulation of Kid, facilitating the Kid-generated polar ejection force. Depletion of NuSAP significantly suppresses the amplitude and velocity of chromosome oscillation.

  12. NUSAP1 may be a crucial biomarker for oral squamous cell carcinoma. down-regulated NUSAP1 expression suppresses tumor proliferation and also enhances anti-tumor effect of paclitaxel by activating apoptotic pathways.

  13. High levels of NuSAP1 expression were related to poor disease-free survival, particularly in triple-negative breast cancer.

  14. A novel association between BRCA1 and NUSAP1 is revealed and a mechanism whereby NUSAP1 is involved in carcinogenesis was elusidated.

  15. High NUSAP1 expression is associated with cervical cancer.

  16. NuSAP is a novel biomarker for prostate cancer recurrence after surgery and its overexpression appears to be driven in part by E2F1 activation

  17. Phosphorylation of NuSAP by Cdk1 is an important mechanism to regulate microtubule dynamics during cell cycle progression.

  18. Interphase NuSAP-chromatin interaction suggests additional functions for NuSAP, as recently identified for other nuclear spindle assembly factors with a role in gene expression or DNA damage response.

  19. NuSAP1 is recognized as an immunogenic antigen in 65% of patients with AML following allogeneic HCT and suggests a tumor antigen role.

Zebrafish Nucleolar and Spindle Associated Protein 1 (NUSAP1) interaction partners

  1. When the in vivo expression of nusap1 was knocked down through antisense oligonucleotide morpholino technology, the morphants of nusap1 showed impaired morphogenesis in the trunk and yolk extension, implying the involvement of Nusap1 in cell migration.

Mouse (Murine) Nucleolar and Spindle Associated Protein 1 (NUSAP1) interaction partners

  1. this work has uncovered an ATM-dependent checkpoint pathway that prevents mitotic progression by targeting a microtubule-associated protein, NuSAP.

NUSAP1 Protein Profile

Protein Summary

NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003

Gene names and symbols associated with NUSAP1

  • nucleolar and spindle associated protein 1 (NUSAP1)
  • nucleolar and spindle associated protein 1 (nusap1)
  • nucleolar and spindle associated protein 1 L homeolog (nusap1.L)
  • nucleolar and spindle associated protein 1 (Nusap1)
  • 2610201A12Rik protein
  • AI481307 protein
  • ankt protein
  • AW547774 protein
  • BB165529 protein
  • BM037 protein
  • fb76a01 protein
  • fi37a11 protein
  • lnp protein
  • NuSAP protein
  • nusap1 protein
  • PRO0310p1 protein
  • Q0310 protein
  • sapl protein
  • sb:cb490 protein
  • wu:fb76a01 protein
  • wu:fi37a11 protein
  • YF-9 protein

Protein level used designations for NUSAP1

nucleolar and spindle-associated protein 1 , nucleolar protein ANKT , nuSAP , Nucleolar and spindle-associated protein 1-B

GENE ID SPECIES
51203 Homo sapiens
567446 Danio rerio
779094 Xenopus laevis
423213 Gallus gallus
475154 Canis lupus familiaris
616028 Bos taurus
108907 Mus musculus
311336 Rattus norvegicus
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