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Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.
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NLP1 functions as an accessory factor in CRM1 (show XPO1 Antibodies)-dependent nuclear protein (show RDBP Antibodies) export
Data show that human nucleoporin (show AGFG2 Antibodies) CG1 (show KTN1 Antibodies) participates in the docking of Vpr at the nuclear envelope, which may contribute to the disruption of the nuclear envelope and to the nuclear import of the viral DNA.
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.
nucleoporin-like protein 2
, NUP42 homolog
, nucleoporin hCG1
, nucleoporin-like protein 1
, nucleoporin-like 2