Nucleoredoxin Proteins (NXN)

Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. Additionally we are shipping Nucleoredoxin Antibodies (42) and Nucleoredoxin Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NXN 18230 P97346
NXN 64359 Q6DKJ4
Rat NXN NXN 360577  
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Top Nucleoredoxin Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$688.00
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$752.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$3,151.50
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$3,162.50
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,213.83
Details

NXN Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, , ,

More Proteins for Nucleoredoxin (NXN) Interaction Partners

Mouse (Murine) Nucleoredoxin (NXN) interaction partners

  1. These results reveal a novel role of NRX in the regulation of PFK1 activity and in the balance between glycolysis and the pentose phosphate pathway.

  2. NRX retains a pool of inactive Dishevelled (show DVL2 Proteins) for robust activation of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling upon Wnt (show WNT2 Proteins) stimulation.

  3. Nucleoredoxin negatively regulates Toll-like receptor 4 (show TLR4 Proteins) signaling via recruitment of flightless-I to myeloid differentiation primary response (show GADD45B Proteins) gene

  4. These data suggest a relationship between the Wnt (show WNT2 Proteins)-beta-catenin (show CTNNB1 Proteins) pathway and redox signalling through redox-sensitive association of NRX with Dvl (show DVL1 Proteins).

  5. formation of a complex between GST-nucleoredoxin, protein phosphatase 2A (PP2A (show PPP2R2B Proteins)) (C) and PP2A (show PPP2R2B Proteins)(D) was demonstrated by pull-down experiments

Human Nucleoredoxin (NXN) interaction partners

  1. identified nucleoredoxin as an interaction partner of Sec63 (show SEC63 Proteins); characterized this interaction; Sec63 (show SEC63 Proteins) is linked to the Wnt (show WNT2 Proteins) signaling pathways and this interaction may be the reason why mutations in SEC63 (show SEC63 Proteins) can lead to polycystic liver disease

  2. Nucleoredoxin is a novel thioredoxin (show TXN Proteins) family member involved in cell growth and differentiation [review]

Xenopus laevis Nucleoredoxin (NXN) interaction partners

  1. Nucleoredoxin regulates the Wnt (show WNT2 Proteins)/planar cell polarity pathway in Xenopus.

Nucleoredoxin (NXN) Protein Profile

Protein Summary

Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).

Gene names and symbols associated with Nucleoredoxin Proteins (NXN)

  • nucleoredoxin (Nxn)
  • nucleoredoxin (NXN)
  • nucleoredoxin S homeolog (nxn.S)
  • nucleoredoxin (nxn)
  • l11Jus13 protein
  • NRX protein
  • ns:zf-es94 protein
  • TRG-4 protein
  • zgc:110449 protein

Protein level used designations for Nucleoredoxin Proteins (NXN)

protein Red-1 , nucleoredoxin 1 , nucleoredoxin

GENE ID SPECIES
18230 Mus musculus
64359 Homo sapiens
360577 Rattus norvegicus
417619 Gallus gallus
444590 Xenopus laevis
531367 Bos taurus
553621 Danio rerio
611162 Canis lupus familiaris
746905 Pan troglodytes
100011801 Monodelphis domestica
100216233 Xenopus (Silurana) tropicalis
100715515 Cavia porcellus
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