NUDT15 Proteins

Mediates the hydrolysis of some nucleoside diphosphate derivatives.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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3 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3084794
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3124647
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2727746
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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NUDT15 Protein Profile

Protein Summary

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.

Gene names and symbols associated with NUDT15

  • nudix hydrolase 15 (NUDT15) antibody
  • nudix (nucleoside diphosphate linked moiety X)-type motif 15 (Nudt15) antibody
  • 6530403O17 antibody
  • A730068G11Rik antibody
  • MTH2 antibody
  • RP11-90M2.1 antibody

Protein level used designations for NUDT15

7,8-dihydro-8-oxoguanine-triphosphatase NUDT15 , 8-oxo-dGTPase NUDT15 , A730068G11Rik , mutT homolog 2 , nucleoside diphosphate-linked moiety X motif 15 , nudix motif 15 , nudix-type motif 15 , probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 , probable 8-oxo-dGTP diphosphatase NUDT15 , MutT homolog 2 , mMTH2

GENE ID SPECIES
55270 Homo sapiens
214254 Mus musculus