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NUMBL Proteins

(Numb Homolog (Drosophila)-Like (NUMBL))

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.

recommended

NUMBL Protein (AA 1-609) (His tag) (ABIN3094283)

Crystallography grade NUMBL Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, Crys, SDS, WB

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recommended

NUMBL Protein (AA 1-604) (His tag) (ABIN3131350)

Crystallography grade NUMBL Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, Crys, SDS, WB

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recommended

NUMBL Protein (Myc-DYKDDDDK Tag) (ABIN2727806)

NUMBL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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NUMBL Proteins by Grade

Find NUMBL Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NUMBL Proteins by Origin

Find NUMBL Proteins for a variety of species such as anti-Human NUMBL, anti-Mouse NUMBL, anti-Rat NUMBL. The species listed below are among those available. Click on a link to go to the corresponding products.

NUMBL Proteins by Source

Find NUMBL Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

NUMBL Proteins by Protein Type

Find NUMBL Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

NUMBL Proteins by Application

Find NUMBL Proteins validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular NUMBL Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

NUMBL Protein (AA 1-609) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3094283

Quantity 1 mg

Datasheet Datasheet

NUMBL Protein (AA 1-604) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3131350

Quantity 1 mg

Datasheet Datasheet

NUMBL Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2727806

Quantity 20 μg

Datasheet Datasheet

NUMBL Protein (AA 1-614) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1475268

Quantity 1 mg

Datasheet Datasheet

Aliases for NUMBL Proteins

NUMB like, endocytic adaptor protein (NUMBL) Proteins
numb homolog-like L homeolog (numbl.L) Proteins
NUMB-like, endocytic adaptor protein (Numbl) Proteins
numb-like (Numbl) Proteins
cag3a Proteins
CAG3A Proteins
ctg3a Proteins
CTG3a Proteins
nbl Proteins
NBL Proteins
numb Proteins
numb-r Proteins
NUMB-R Proteins
numblike Proteins
NUMBLIKE Proteins
numbr Proteins
NUMBR Proteins
tnrc23 Proteins
TNRC23 Proteins

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NUMBL Proteins by Grade

NUMBL Proteins by Origin

NUMBL Proteins by Source

NUMBL Proteins by Protein Type

NUMBL Proteins by Application

Popular NUMBL Proteins

Aliases for NUMBL Proteins

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