anti-ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) Antibodies

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity). Additionally we are shipping ORAI2 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ORAI2 80228 Q96SN7
ORAI2 269717 Q8BH10
ORAI2 304592  
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Top anti-ORAI2 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ORAI2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with ORAI2 antibody ABIN214005 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Placenta (formalin-fixed, paraffin-embedded) stained with ORAI2 antibody ABIN214005 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 8 to 11 Days
$474.10
Details
Human Rabbit Un-conjugated ICC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$527.03
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB ORAI2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB Western Blot: Orai2 Antibody [NBP1-77283] - Analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL. Immunocytochemistry: Orai2 Antibody [NBP1-77283] - ORAI2 in Jurkat cells with ORAI2 antibody at 5 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$488.73
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Orai2 Antibody [NBP2-19630] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:500 dilution. Western Blot: Orai2 Antibody [NBP2-19630] - Sample (30 ug of whole cell lysate) A: H1299 12% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details

Top referenced anti-ORAI2 Antibodies

  1. Human Polyclonal ORAI2 Primary Antibody for IF, WB - ABIN541303 : Lewis: Calcium signaling mechanisms in T lymphocytes. in Annual review of immunology 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ORAI2 Primary Antibody for ICC, ELISA - ABIN1002946 : Soboloff, Spassova, Dziadek, Gill: Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication. in Biochimica et biophysica acta 2006 (PubMed)
    Show all 3 Pubmed References

More Antibodies against ORAI2 Interaction Partners

Human ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) interaction partners

  1. ORAI1-3, are preferentially expressed in proximal tubular epithelial cells and downregulated in patients with diabetic nephropathy.

  2. findings provide evidence for a role for Orai1 and Orai2, in SOCE and migration in the human HL60 promyeloblastic cell line

  3. results identified the ORAI-NOX2 feedback loop as a determinant of monocyte immune responses.

  4. Orai1, Orai2 and STIM1 form functional Ca(2+) release-activated Ca(2+) channels in OUMS-27 cells (chondrocytes) and that these complexes are responsible for sustained Ca(2+) entry in response to agonist stimulation.

  5. The higher amplitude of store-operated Ca2+ entry was associated to the over-expression for Stim2, Orai2-3, and TRPC1 while Stim2 levels remained constant and Stim1, Orai1, Orai3, TRPC1 and TRPC4 proteins were over-expressed in primary myelofibrosis.

  6. Orai1 but not Orai2 plays a major role in the influx of extracellular Ca2+ into and mediator release from HLMCs following their activation

  7. Orai1 and Orai2 operate in a STIM-dependent manner, Orai3 does not interact with STIM isoforms upon calcium store depletion in platelets.

  8. With these data we show a new Ca(2)(+) entry pathway linked to the Ca(2)(+)/inositolphosphate second-messenger system in RPE cells which help to further understand regulatory pathways of agonists.

  9. Results suggest that Orai1, -2, and -3 channels are similarly inhibited by extracellular calcium, indicating similar affinities for Ca(2+) within the selectivity filter.

  10. The effects of 2-aminoethoxydiphenyl borate on orai1, orai2, orai3 metabolism in HEK293 cells with and without STIM1 are reported.

  11. analysis of activation of Orai1-3 channels by a STIM1 coiled-coil mutant

  12. Data show that the fast Ca(2+)-dependent inactivation is mediated by three conserved glutamates in the C termini (CT) of Orai2 and Orai3, which show prominent fast Ca(2+)-dependent inactivation compared with Orai1.

Mouse (Murine) ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) interaction partners

  1. Orai2 proteins contribute to Ca(2+) entry in connective tissue type mast cells in discrete operation modes depending on the availability of calcium ions in the extracellular space.

  2. ORAI1 and ORAI2 form heteromeric Ca(2+) release-activated Ca(2+) channels, in which ORAI2 fine-tunes the magnitude of Store-operated Ca(2+) entry to modulate immune responses.

  3. This study demonstrated that Transient Receptor Potential Canonical 6 (TRPC6) and Orai2 form stromal interaction molecule 2 (STIM2)-regulated neuronal-store-operated Ca(2+) influx (nSOC) channel complex in hippocampal synapse and the resulting Ca(2+) influx is critical for long-term maintenance of mushroom spines in hippocampal neurons.

  4. results identified the ORAI-NOX2 feedback loop as a determinant of monocyte immune responses.

  5. The data from this study indicate that upregulation of STIM2 and Orai2 is involved in the phenotypic transition of pulmonary arterial smooth muscle cells from a contractile state to a proliferative state.

  6. Data indicate that the Ca(2+) release-activated Ca(2+) channels (CRAC) blocker GSK-7975A inhibited store-operated Ca(2+) entry in a concentration-dependent manner.

Cow (Bovine) ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) interaction partners

  1. Orai2 is specifically up-regulated during the G2/M phase, negatively modulates the store-operated Ca(2+) entry activity, and may contribute to the regulation of cell cycle progression in brain capillary endothelial cells.

ORAI2 Antigen Profile

Protein Summary

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity).

Gene names and symbols associated with ORAI2

  • ORAI calcium release-activated calcium modulator 2 (ORAI2) antibody
  • ORAI calcium release-activated calcium modulator 2 (Orai2) antibody
  • ORAI calcium release-activated calcium modulator 2 S homeolog (orai2.S) antibody
  • ORAI calcium release-activated calcium modulator 2 (orai2) antibody
  • A730041O15Rik antibody
  • C7orf19 antibody
  • CBCIP2 antibody
  • LOC100230993 antibody
  • MEM142B antibody
  • orai-1 antibody
  • orai1 antibody
  • ORAI2 antibody
  • RGD1310213 antibody
  • tmem142a antibody
  • tmem142b antibody

Protein level used designations for ORAI2

CAP-binding protein complex interacting protein 2 , CAP-binding protein complex-interacting protein 2 , H_NH0514P08.8 , protein orai-2 , putative protein ORAI2-2 , transmembrane protein 142B , calcium release-activated calcium channel 2 , calcium release-activated calcium modulator 2 protein , ORAI calcium release-activated calcium modulator 2 , calcium release-activated calcium channel protein 1 , protein orai-1 , transmembrane protein 142A

GENE ID SPECIES
80228 Homo sapiens
269717 Mus musculus
304592 Rattus norvegicus
417509 Gallus gallus
463930 Pan troglodytes
511233 Bos taurus
608106 Canis lupus familiaris
734537 Xenopus laevis
100230993 Taeniopygia guttata
100359269 Oryctolagus cuniculus
100380109 Xenopus (Silurana) tropicalis
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