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ORAI2 Products

(ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Categories

Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1 (By similarity).

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Featured ORAI2 Categories

ORAI2 Antibodies

High quality antibodies with extensive validation data.

ORAI2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ORAI2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Human, Monkey, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6738675
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, EIA
Validations
  • (2)
Cat. No. ABIN500423
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC
Validations
  • (2)
Cat. No. ABIN7043414
Quantity 50 μL
Datasheet Datasheet

Recommended ORAI2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6220220
Quantity 96 tests
Datasheet Datasheet

Recommended ORAI2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313644
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3105683
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3124755
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ORAI2 products

Cox, Hussell, Søndergaard, Roepstorff, Bui, Deer, Zhang, Li, Lamberth, Kvist, Padkjær, Haase, Zahn, Odegard: "Antibody-mediated targeting of the Orai1 calcium channel inhibits T cell function." in: PLoS ONE, Vol. 8, Issue 12, pp. e82944, (2013) (PubMed).

Potier, Gonzalez, Motiani, Abdullaev, Bisaillon, Singer, Trebak: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).

Liao, Erxleben, Yildirim, Abramowitz, Armstrong, Birnbaumer: "Orai proteins interact with TRPC channels and confer responsiveness to store depletion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 11, pp. 4682-7, (2007) (PubMed).

DeHaven, Smyth, Boyles, Putney: "Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels." in: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17548-56, (2007) (PubMed).

Soboloff, Spassova, Dziadek, Gill: "Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication." in: Biochimica et biophysica acta, Vol. 1763, Issue 11, pp. 1161-8, (2006) (PubMed).

Mercer, Dehaven, Smyth, Wedel, Boyles, Bird, Putney: "Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1." in: The Journal of biological chemistry, Vol. 281, Issue 34, pp. 24979-90, (2006) (PubMed).

Navas-Martín, Weiss: "Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development." in: Journal of neurovirology, Vol. 10, Issue 2, pp. 75-85, (2004) (PubMed).

Lewis: "Calcium signaling mechanisms in T lymphocytes." in: Annual review of immunology, Vol. 19, pp. 497-521, (2001) (PubMed).

Synonyms and alternative names related to ORAI2

ORAI calcium release-activated calcium modulator 2 (ORAI2), ORAI calcium release-activated calcium modulator 2 (Orai2), ORAI calcium release-activated calcium modulator 2 S homeolog (orai2.S), ORAI calcium release-activated calcium modulator 2 (orai2), A730041O15Rik, C7orf19, CBCIP2, LOC100230993, MEM142B, orai-1, orai1, ORAI2, RGD1310213, tmem142a, TMEM142B, Tmem142b, tmem142b

Protein level used designations for ORAI2

  • CAP-binding protein complex interacting protein 2
  • CAP-binding protein complex-interacting protein 2
  • H_NH0514P08.8
  • protein orai-2
  • putative protein ORAI2-2
  • transmembrane protein 142B
  • calcium release-activated calcium channel 2
  • calcium release-activated calcium modulator 2 protein
  • ORAI calcium release-activated calcium modulator 2
  • calcium release-activated calcium channel protein 1
  • protein orai-1
  • transmembrane protein 142A
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