anti-Oligodendrocyte Transcription Factor 1 (OLIG1) Antibodies

Promotes formation and maturation of oligodendrocytes, especially within the brain. Additionally we are shipping OLIG1 Kits (8) and OLIG1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OLIG1 116448 Q8TAK6
OLIG1 50914 Q9JKN5
OLIG1 60394 Q9WUQ3
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Top anti-OLIG1 Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-OLIG1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Thymus 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Olig1 Antibody Titration: 1.0 ug/ml Positive Control: Rat Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (fro), WB IHC-Fr Image OLIG1 antibody [C2C3] detects OLIG1 protein on adult mouse brain by immunohistochemical analysis. Sample: Frozen section of adult mouse brain. Red: OLIG1 antibody [C2C3] , diluted at 1:200. Blue: DAPI WB Image Sample (30 ug of whole cell lysate) A: Molt-4 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with OLIG1 antibody ABIN291782 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-OLIG1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p), WB Human Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-OLIG1 antibody IHC of human endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis OLIG1 using HuvEc whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC, IHC (fro), WB Western Blot: Olig1 Antibody [NBP1-31018] - Sample (30 ug of whole cell lysate) A: Molt-4 12% SDS PAGE; antibody diluted at 1:1000. 100 μL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Mouse Rabbit Un-conjugated WB OLIG1 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OLIG1 antibody detected the OLIG1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details

Top referenced anti-OLIG1 Antibodies

  1. Mammalian Monoclonal OLIG1 Primary Antibody for ISt, IHC - ABIN1304878 : Vierbuchen, Ostermeier, Pang, Kokubu, Südhof, Wernig: Direct conversion of fibroblasts to functional neurons by defined factors. in Nature 2010 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Polyclonal OLIG1 Primary Antibody for ICC, IF - ABIN447417 : Motizuki, Isogaya, Miyake, Ikushima, Kubota, Miyazono, Saitoh, Miyazawa: Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β. in The Journal of biological chemistry 2013 (PubMed)

More Antibodies against OLIG1 Interaction Partners

Human Oligodendrocyte Transcription Factor 1 (OLIG1) interaction partners

  1. Olig1 has a critical function in regulation of postnatal neural progenitor cell production in response to Noggin.

  2. This study demonstrated that increased expression of mRNA of OLIG1 in ventral prefrontal white matter in major depressive disorder.

  3. Olig1 is a Smad cofactor involved in TGF-beta-induced cell motility

  4. This study review OLIG1 have developmental functions in patterning, neuron subtype specification and the formation of oligodendrocytes and play the role in the postnatal brain during repair processes and in neurological disease states.

  5. Olig1 was not expressed in freshly isolated oligodendrocytes, but is expressed from the beginning of process extension until membrane maintenance.

  6. analysis of conserved and non-conserved functional elements at the Olig1 and Olig2 locus

  7. Olig1 and Olig2 transcription factors in the human central nervous system are important not only for differentiation of the oligodendrocyte lineage, but they may also have a role in neural cell specification.

  8. identified novel coding variants in the Olig1 gene, including a trinucleotide repeat, but found no evidence to support the hypothesis that genetic variation in Olig1 influences susceptibility to multiple sclerosis

  9. Mutations in OLIG1 and OLIG2 are not likely to be associated with this subgroup of hypomyelinating disorders.

  10. OLIG1 protein expression significantly correlates with overall survival in non-small cell lung cancer patients

  11. No significan correlation was found between proliferation index in pilocytic astrocytomas and Olig-1 expression.

Mouse (Murine) Oligodendrocyte Transcription Factor 1 (OLIG1) interaction partners

  1. found that many of the Olig2-bound sites were associated with genes with biological processes corresponding to OL differentiation (Nkx2.2, Nkx6.2, and Sip1), myelination and ensheathment (Mbp, Cldn11, and Mobp), as well as cell cycle and cytoskeletal regulation

  2. the dynamic interplay between HMGNs and H1 in chromatin epigenetically regulates the expression of OLIG1&2, thereby affecting oligodendrocyte development and myelination, and mouse behavior.

  3. Olig1 begins to be expressed at the ventral domain of the otocyst at embryonic day (E) 9.5, and Olig1 expression in the epithelium of the developing inner ear persists to E15.5.

  4. These studies establish that acetylation of Olig1 regulates its chromatin dissociation and subsequent translocation to the cytoplasm and is required for its function in oligodendrocyte maturation.

  5. The current study demonstrates a unique role for Olig1 in promoting oligodendrocyte progenitor cell commitment, differentiation, and subsequent myelination primarily in brain, but not spinal cord.

  6. Our findings support the original conclusion that Olig1 plays a minor and non-essential role in oligodendrocyte development.

  7. The results of this study establish Olig1 as an essential repressor of Dlx1/2 and interneuron production in developing mammalian brain.

  8. Olig1 is a Smad cofactor involved in TGF-beta-induced cell motility

  9. Our results suggest a novel role for a phosphorylated cytosolic Olig1 in membrane expansion and maturation of oligodendrocytes.

  10. Olig1function is required for the remyelination potential of neural stem cells after transplant, through specification and/or maintenance of oligodendroglial identity.

  11. analysis of conserved and non-conserved functional elements at the Olig1 and Olig2 locus

  12. 10% of Olig1 deficient mice delayed onset of experimental autoimmune encephalomyelitis.

  13. Olig1 and Olig2, two genes that are triplicated in Down syndrome were overexpressed in a widely used model of Down syndrome

  14. In the spinal cord, Olig1, Olig2 and proneural genes comprise a combinatorial code for the specification of neurons, astrocytes, and oligodendrocytes.

  15. Olig1 has a role in inducing differentiation of neural stem cells into oligodendrocyte progenitor cells

  16. findings show that Olig1 function in mice is required not to develop the brain but to repair it; demonstrated a genetic requirement for Olig1 in repairing the types of lesions that occur in patients with multiple sclerosis

  17. Olig1 regulates transcription of the major myelin-specific genes, Mbp, Plp1, and Mag, and suppresses expression of a major astrocyte-specific gene, Gfap. Olig1 is a central regulator of oligodendrocyte myelinogenesis in brain.

  18. The expression of nuclear Olig1 was inhibited when mouse oligodendrocyte progenitor cells were cultured in the absence of insulin.

  19. Data show that both Olig1 transcription and Olig1 protein expression are downregulated during oligodendrocyte progenitor cell differentiation.

OLIG1 Antigen Profile

Protein Summary

Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).

Gene names and symbols associated with OLIG1

  • oligodendrocyte transcription factor 1 (OLIG1) antibody
  • oligodendrocyte transcription factor 1 (Olig1) antibody
  • AI836478 antibody
  • AW494459 antibody
  • Bhlhb6 antibody
  • bHLHe21 antibody
  • Olg-1 antibody
  • Olg1 antibody
  • OLIG1 antibody
  • Oligo1 antibody

Protein level used designations for OLIG1

oligodendrocyte transcription factor 1 , basic domain, helix-loop-helix protein, class B, 6 , class B basic helix-loop-helix protein 6 , class E basic helix-loop-helix protein 21 , oligo1 , oligodendrocyte lineage transcription factor 1 , oligodendrocyte-specific bHLH transcription factor 1 , Olg-1 bHLH protein

GENE ID SPECIES
539307 Bos taurus
458513 Pan troglodytes
100137243 Papio anubis
116448 Homo sapiens
487736 Canis lupus familiaris
50914 Mus musculus
60394 Rattus norvegicus
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