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Transcriptional activator. Additionally we are shipping and many more products for this protein.
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Human Monoclonal ONECUT3 Primary Antibody for IHC, ELISA - ABIN1724872
Vanhorenbeeck, Jacquemin, Lemaigre, Rousseau: OC-3, a novel mammalian member of the ONECUT class of transcription factors. in Biochemical and biophysical research communications 2002
OC-3 is required for development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.
Data show that Onecut-2/Onecut-3 double knockout is a perinatal lethal.
Our data unveil a complex and dynamic expression profile of the OC proteins in spinal MN, which suggests that these factors may participate in regulatory networks that control different steps of motor neuron development.
hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm
In conclusion, CD44 and Oct3/4 overexpression may imply malignant transformation of pancreatic ducts and could help pathologists make a more accurate diagnosis and decision on clear surgical margins.
Transcriptional activator. Binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR (By similarity).
one cut domain family member 3
, one cut homeobox 3
, transcription factor ONECUT-3
, one cut domain, family member 3