anti-PARK2 Co-Regulated (PACRG) Antibodies

PACRG encodes a protein that is conserved across metazoans. Additionally we are shipping PARK2 Co-Regulated Kits (6) and PARK2 Co-Regulated Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PACRG 135138 Q96M98
PACRG 499021  
PACRG 69310 Q9DAK2
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Top anti-PARK2 Co-Regulated Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PACRG Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated EIA, WB   0.1 mg 4 to 8 Days
$632.50
Details
Chicken Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with PACRG antibody ABIN213842 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PACRG antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB PACRG Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PACRG antibody detected the PACRG protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using  Affinity Purified anti-PACRG antibody shows detection of a band ~40 kDa corresponding to human PACRG (arrowhead lane 1). Specific reactivity with this band is blocked when the antibody is pre-incubated with the immunizing peptide (lane 2). Approximately 35 ug of a mouse embryonic fibroblast (MEF) whole cell lysate was separated by 4-20% SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:1,500 for 2h at room temperature followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX  for 45 min at room temperature. IRDye800 fluorescence image was captured using the Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 100 μg 5 to 7 Days
$598.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of PACRG expression in transfected 293T cell line by PACRG MaxPab polyclonal antibody.Lane 1: PACRG transfected lysate(28.27 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 50 μg 6 to 8 Days
$495.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using PACRG polyclonal antibody  shows detection of aband ~ 40 KDa corresponding to human PACRG (arrowhead lane 1). Specific reactivity with this bandis blocked when the antibody is pre-incubated withthe immunizing peptide (Lane 2). Approximately 35 ug of a mouse embryonic fibroblast (MEF) whole cell lysate was separated by 4-20% SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:1,500 for 2h at room temperature followed by washes and reaction with a 1 : 10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX for 45 min at room temperature. IRDye™800 fluorescence image was captured usingthe Odyssey® Infrared Imaging System developed byLI-COR. IRDye is a trademark of LI-COR, Inc. 100 μg 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated WB PACRG antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details

Top referenced anti-PARK2 Co-Regulated Antibodies

  1. Cow (Bovine) Polyclonal PACRG Primary Antibody for WB - ABIN2785168 : Verrengia Guerrero, Taylor, Simkiss: Modelling 2,4-dichlorophenol bioavailability and bioaccumulation by the freshwater fingernail clam Sphaerium corneum using artificial particles and humic acids. in Environmental pollution (Barking, Essex : 1987) 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against PARK2 Co-Regulated Interaction Partners

Human PARK2 Co-Regulated (PACRG) interaction partners

  1. Mapping of the PARK2 and PACRG gene regulatory region with 96 SNPs, with a resolution of 1 SNP per 1 Kb for PARK2 gene regulatory region in a North Indian population, showed an involvement of 11 SNPs in determining the susceptibility towards leprosy.

  2. PARK2 and PACRG are commonly downregulated in clear-cell renal cell carcinoma and are associated with aggressive disease and poor clinical outcome.

  3. conducted high-density association mapping of PARK2/PACRG SNPs with leprosy and identified 69 SNPs significantly associated with leprosy in 198 single-case Vietnamese leprosy families

  4. Elevated levels of PACRG result in increased neuronal autophagy.

  5. single nucleotide polymorphisms of PARK2 with leprosy susceptibility in Chinese population

  6. the association of polymorphisms rs9356058 and rs1040079 in gene PARK2/PACRG with leprosy

  7. Mutation of PACRG was not identified as a cause of male infertility, but variation in the promoter was demonstrated to be a risk factor associated with azoospermia.

  8. PINK1, Omi/HtrA2 and parkin participate at different levels in mitochondrial quality control, converging through some overlapping and some distinct steps to maintain a common phenotype of healthy mitochondrial networks [REVIEW]

  9. PACRG is linked to parkin via a bi-directional promoter

  10. Glup/PACRG forms a large molecular chaperone complex, suppresses cell death induced by accumulation of unfolded Pael receptor, facilitates the formation of Pael-R inclusions,and is a component of Lewy bodies in Parkinson's disease

  11. Variants in the regulatory region shared by PARK2 and PACRG therefore act as common risk factors for leprosy

  12. mutation of PACRG plays little or no role in the development of early-onset parkinsonism

  13. candidate tumor suppressor genes PARK2 and PACRG are epigenetically regulated in human leukemia, suggesting that abnormal methylation and regulation of PARK2 and PACRG may play a role in the pathogenesis and development of this hematological neoplasm

  14. Suspected association of SNP's with leprosy is not borne out in Indian population.

  15. PACRG is regulated by the ubiquitin-proteasomal system and may play a role in the pathogenesis of Parkinson's disease.

  16. The observed features of genotypic distribution by PACRG marker point to the influence of the considered marker on the incidence of tuberculosis.

  17. Thw results of this study suggested that point mutations in PACRG are not a common cause of EO-PD but haploinsufficiency for PACRG may be associated with disease.

Mouse (Murine) PARK2 Co-Regulated (PACRG) interaction partners

  1. Studies demonstrate that MEIG1/PACRG forms a complex in the manchette and that this complex is necessary to transport cargos, such as SPAG16L, to build the sperm flagella.

  2. Pacrg is required for motile cilia function and may be involved in the pathogenesis of hydrocephalus.

  3. Findings reveal a critical role for the MEIG1/PARCG partnership in manchette structure and function and the control of spermiogenesis.

  4. PACRG is linked to parkin via a bi-directional promoter [PACRG]

  5. The quaking mutation is a deletion of approximately 1.17 Mb of mouse chromosome 17, resulting in the deletion of the entire promoter and first five coding exons of PRKN. The recently described Parkin Co-Regulated Gene (PACRG) is completely deleted.

  6. Results demonstrate that the deletion of Pacrg (PARKIN-coregulated gene) is the cause of male sterility in the Quaking(viable) (qk(v)) mutant mouse.

  7. These results suggest that the transcriptional co-regulation of Pacrg and parkin leads to a similar regional protein distribution in mouse brain, which may have functional significance for the two proteins.

  8. The results of this study indicated that expression of Pacrg in the cells associated with the cerebral ventricle, in addition to the aqueduct of Sylvius and choroid plexus. And strong expression was observed since newborn period to adulthood.

  9. Pacrg is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.

PARK2 Co-Regulated (PACRG) Antigen Profile

Protein Summary

This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PACRG

  • parkin coregulated (PACRG) antibody
  • PARK2 co-regulated (pacrg) antibody
  • parkin coregulated (Pacrg) antibody
  • PARK2 coregulated (PACRG) antibody
  • PARK2 co-regulated (Pacrg) antibody
  • PARK2 co-regulated (PACRG) antibody
  • 1700008H23Rik antibody
  • GLUP antibody
  • HAK005771 antibody
  • PACRG antibody
  • PARK2CRG antibody
  • RGD1561027 antibody
  • RP3-495O10.2 antibody
  • zgc:101786 antibody

Protein level used designations for PACRG

PARK2 co-regulated , molecular chaperone/chaperonin-binding protein , parkin co-regulated gene protein , parkin coregulated gene protein , PARK2 coregulated gene protein , hypertension-related protein 1-like protein , parkin coregulated gene protein homolog

GENE ID SPECIES
484071 Canis lupus familiaris
704457 Macaca mulatta
741393 Pan troglodytes
135138 Homo sapiens
492757 Danio rerio
499021 Rattus norvegicus
421576 Gallus gallus
69310 Mus musculus
767959 Bos taurus
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