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Microtubule-binding protein essential for faithful chromosome segregation. Additionally we are shipping PINX1 Proteins (14) and PINX1 Kits (6) and many more products for this protein.
Showing 10 out of 82 products:
Human Polyclonal PINX1 Primary Antibody for ELISA, WB - ABIN565796
Ma, Wu, Liu, Xu, Li, Li: The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population. in Journal of cancer research and clinical oncology 2009
Show all 4 Pubmed References
Human Polyclonal PINX1 Primary Antibody for ELISA, WB - ABIN257850
Zhou, Lu: The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. in Cell 2001
Human Polyclonal PINX1 Primary Antibody for ELISA, WB - ABIN4345693
Banik, Counter: Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. in The Journal of biological chemistry 2004
Low PINX1 expression is associated with colorectal cancer cell migration, invasion and metastasis
PinX1 silencing in CD133+ CSCs significantly decreased TRF1 (show TERF1 Antibodies), Mad1 (show MXD1 Antibodies), and p53 (show TP53 Antibodies) mRNA levels, while it increased hTERT and c-Myc (show MYC Antibodies) mRNA levels.
NF-kappaB (show NFKB1 Antibodies) p65 (show GORASP1 Antibodies) potentiated tumor growth via suppressing a novel target LPTS
Our findings suggested that PinX1 could be a potential tumour suppressor in non-small-cell lung cancer and that loss of PinX1 promoted non-small-cell lung cancer progression.
Low expression of PinX1 is associated with malignant behavior in basal-like breast cancer.
The cost-effective expression of PinX1 could constitute a novel molecular predictor/marker for NSCLC management.
PINX1 Polymorphisms are associated with Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection.
The stability of PinX1 is maintained in nucleolus in the presence of TERT (show TERT Antibodies).
PinX1 negatively regulated ccRCC metastasis and the expression of MMP-2 (show MMP2 Antibodies) and NF-kappaB (show NFKB1 Antibodies)-p65 (show GORASP1 Antibodies)
High PinX1 expression significantly correlated with a worse 5-year overall and disease-specific survival in gliomas.
PinX1 heterozygosity and PinX1 knockdown in mouse embryonic fibroblasts activated telomerase and led to concomitant telomerase-dependent chromosomal instability.
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity).
PIN2-interacting protein 1
, 67-11-3 protein
, PIN2 interacting protein 1
, PIN2/TERF1-interacting telomerase inhibitor 1
, TRF1-interacting protein 1
, hepatocellular carcinoma-related putative tumor suppressor
, liver-related putative tumor suppressor
, pin2-interacting protein X1
, protein 67-11-3
, PIN2-interacting protein X1
, PIN2/TRF1-interacting protein
, Pin2-interacting protein X1