PINX1 Products
(PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
Categories
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity).
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Featured PINX1 Categories
PINX1 Antibodies
High quality antibodies with extensive validation data.
PINX1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PINX1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PINX1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (2)
Cat. No.
ABIN565796
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6264227
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7163457
Quantity
100 μg
Datasheet
Datasheet
Recommended PINX1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1148151
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1148152
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1148153
Quantity
96 tests
Datasheet
Datasheet
Recommended PINX1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124453
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315118
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5570477
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PINX1 products
: "PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway." in: Angiogenesis, (2019) (PubMed).: "The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis." in: Genomics, Vol. 105, Issue 1, pp. 5-16, (2014) (PubMed).
: "Plk1-mediated mitotic phosphorylation of PinX1 regulates its stability." in: European journal of cell biology, Vol. 89, Issue 10, pp. 748-56, (2010) (PubMed).
: "The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population." in: Journal of cancer research and clinical oncology, Vol. 135, Issue 3, pp. 431-7, (2009) (PubMed).
: "PinX1 is recruited to the mitotic chromosome periphery by Nucleolin and facilitates chromosome congression." in: Biochemical and biophysical research communications, Vol. 384, Issue 1, pp. 76-81, (2009) (PubMed).
: "Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 51745-8, (2004) (PubMed).
: "The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor." in: Cell, Vol. 107, Issue 3, pp. 347-59, (2001) (PubMed).
Synonyms and alternative names related to PINX1
PIN2/TERF1 interacting telomerase inhibitor 1 (PINX1), PIN2/TERF1 interacting, telomerase inhibitor 1 (PINX1), PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), 67-11-3, 2210403I16Rik, 2610028A01Rik, AU024023, LPTL, LPTS, LPTS1, PINX1, RGD1566025Protein level used designations for PINX1
- PIN2-interacting protein 1
- 67-11-3 protein
- PIN2 interacting protein 1
- PIN2/TERF1-interacting telomerase inhibitor 1
- TRF1-interacting protein 1
- hepatocellular carcinoma-related putative tumor suppressor
- liver-related putative tumor suppressor
- pin2-interacting protein X1
- protein 67-11-3
- PIN2-interacting protein X1
- PIN2/TRF1-interacting protein
- Pin2-interacting protein X1
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