POU Class 3 Homeobox 2 (POU3F2) ELISA Kits

POU3F2 encodes a member of the POU-III class of neural transcription factors. Additionally we are shipping POU3F2 Antibodies (82) and POU3F2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
POU3F2 5454 P20265
POU3F2 18992 P31360
POU3F2 29588 P56222
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Top POU3F2 ELISA Kits at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 11 to 18 Days
$618.29
Details
Mouse
  96 Tests 15 to 18 Days
$875.60
Details
Rat
  96 Tests 15 to 18 Days
$875.60
Details

More ELISA Kits for POU3F2 Interaction Partners

Human POU Class 3 Homeobox 2 (POU3F2) interaction partners

  1. These results suggest that the proliferative population within melanoma tumors express MITF, and both MITF and BRN2 are important for metastatic growth in vivo. This finding highlights the importance of BRN2 and MITF expression in development of melanoma metastasis.

  2. CDKN2A suppresses the initiation of melanoma invasion through inhibition of BRN2.

  3. BRN2 also suppresses an apoptosis-associated gene expression program to protect against UVB-, chemotherapy- and vemurafenib-induced apoptosis. Remarkably, BRN2 expression also correlates with a high single-nucleotide variation prevalence in human melanomas

  4. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation.

  5. Re4sults show that BRN2 is: directly transcriptionally repressed by AR, required for the expression of terminal neuroendocrine markers and aggressive growth of castration-resistant prostate cancer (CRPC), and is highly expressed in human neuroendocrine prostate cancer and metastatic CRPC with low circulating PSA.

  6. These findings not only shed light on the molecular mechanism of the anticancer properties of capsaicin, but also the transcription regulation of tNOX expression that may potentially explain how POU3F2 is associated with tumorigenesis.

  7. Data indicate that NFIB protein increases EZH2 protein expression downstream of BRN2 protein, which further decreases MITF protein levels.

  8. We show that POU3F2 lies downstreamof SIM1 and controls oxytocin expression in the hypothalamic neuroendocrine preoptic area. We show that this finding is consistent with the expression patterns of POU3F2 and related genes in the human brain.

  9. BRN2 is a higher level regulator than ASCL1 and ND1 and BRN2 might be involved in aggressiveness of small cell lung cancer.

  10. TTF1 expression in small-cell lung cancer is a cell lineage-specific phenomenon that involves the developing neural cell-specific homeoprotein BRN2.

  11. The present study investigated transcriptional regulation of CDH13 in melanoma. Found an inverse correlation between BRN2 and T-cadherin protein and transcript expression in melanoma.

  12. PI3K has a crucial role in regulating Brn-2 and Pax3 expression and neoplasm invasiveness, and it is a key determinant of melanoma subpopulation diversity.

  13. links BRN2 as an activator and MITF as a repressor of the NOTCH pathway in melanoma cells. Loss of the BRN2-MITF axis in antisense-ablated cell lines decreased the melanoma sphere-forming capability and cell adhesion

  14. a model for the apparent non-overlapping expression levels of BRN2 and MITF in melanoma, mediated by miR-211 expression.

  15. POU3F2 may regulate the properties of melanoma cells via autocrine KIT ligand signalling.

  16. The results suggest that the high levels of Brn-2 expression observed in melanomas link BRAF signaling to increased proliferation.

  17. Rb induces a proliferative arrest and regulates Brn-2 expression in retinoblastoma cells

  18. Brn-2 regulates invasiveness and directly represses Mitf expression.

  19. SOX9 and SOX10 but not BRN2 seem to be required for nestin expression in human melanoma.

  20. Expression and purification of full-length BRN2, a transcription factor involved in melanoma growth, are reported.

Mouse (Murine) POU Class 3 Homeobox 2 (POU3F2) interaction partners

  1. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation.

  2. that POU3F2 is involved in cognitive function as well as adult hippocampal neurogenesis

  3. This study investigated changes in the skin in the K5-Brn2 transgenic mouse, which overexpresses Brn2 and contains the keratin 5 promotor. The volume of the eccrine glands was reduced in the K5-Brn2 transgenic mouse.

  4. results suggest that a mutually repressive mechanism exists between Brn1/2 and Rorb expression and that the established expression of Brn1/2 and Rorb further specifies those neurons into L2/3 and L4, respectively, during UCP maturation

  5. Mammalian-specific sequences in pou3f2 contribute to maternal behavior.

  6. Brn2-Zic1 axis is essential to specify neural fate in retinoic-acid-treated embryonic stem cells.

  7. Brn2 predominantly forms homodimers on MORE cis elements in NS5 mouse neural stem cells

  8. This study showed that Sox/Pou cis-regulatory logics and heterogeneity of cortical progenitors in the the mouse embryonic cerebral cortex.

  9. Onset of Pou3f2 expression occurs in ventricular zone progenitors, and that Pou3f2 subsequently label neural progeny switching from deep-layer Ctip2+ identity to Satb2+ upper-layer fate as they migrate to proper superficial positions.

  10. Our findings have important implications for understanding lineage specification and somatic cell reprogramming, where SOX2, OCT4, and BRN2 have been shown to be key factors

  11. Melanocyte migration and proliferation are controlled both through the regulation of Pax3 by nonphosphorylated Brn2 and through the regulation of MITF-M by the overall BRN2 level.

  12. In the brains of Huntington's disease model mice, Brn-2 loses its function through two pathways, its sequestration by mutant huntingtin and its reduced transcription, leading to reduced expression of hypothalamic neuropeptides.

  13. Brn-1 and Brn-2 appear to critically control the initiation of radial migration, redundantly regulating the cell-autonomous expression of the p35 and p39 regulatory subunits of Cdk5 in migrating cortical neurons

  14. Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocrotical neurons

  15. Brn-2 function largely overlaps with that of Oct-6 in driving the transition from promyelinating to myelinating Schwann cells

  16. Data show that Brn-2 is expressed in melanocytes but not in embryonic melanoblasts and that its expression is directly controlled by the Wnt/beta-catenin signaling pathway in melanoma cell lines and in transgenic mice.

  17. The results suggest that the high levels of Brn-2 expression observed in melanomas link BRAF signaling to increased proliferation.

  18. Data support the model that synergistic interactions between group B1/C SOX (SOX1/2/3, SOX11) and class III POU (Brn2)within the nucleus determine Nestin expression.

  19. the interaction between Brn-2 and Jab1 may provide some insights into the understanding of neuronal development and neurodegenerative diseases

  20. Paired-type and POU homeodomain-containing transcription factors Otx2 and Brn2 together appear to play a common role in regulating gene expression in retinal bipolar cells.

Zebrafish POU Class 3 Homeobox 2 (POU3F2) interaction partners

  1. Using morpholino and mutant zebrafish models, we show that POU3F2 lies downstream of SIM1 and controls oxytocin expression in the hypothalamic neuroendocrine preoptic area.

POU3F2 Antigen Profile

Antigen Summary

This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

Gene names and symbols associated with POU3F2

  • POU class 3 homeobox 2 (POU3F2) antibody
  • POU class 3 homeobox 2 L homeolog (pou3f2.L) antibody
  • POU domain, class 3, transcription factor 2 (Pou3f2) antibody
  • POU class 3 homeobox 2 S homeolog (pou3f2.S) antibody
  • POU class 3 homeobox 2 (Pou3f2) antibody
  • POU class 3 homeobox 2b (pou3f2b) antibody
  • POU class 3 homeobox 2a (pou3f2a) antibody
  • 9430075J19Rik antibody
  • A230098E07Rik antibody
  • brn-1.2 antibody
  • Brn-2 antibody
  • brn1.2 antibody
  • Brn2 antibody
  • id:ibd5088 antibody
  • N-Oct3 antibody
  • oct-7 antibody
  • OCT7 antibody
  • OTF-7 antibody
  • Otf7 antibody
  • pou3f2 antibody
  • pou3f2-A antibody
  • pou3f4 antibody
  • pou47 antibody
  • POUF3 antibody
  • XlPOU3 antibody
  • XLPOU3b antibody
  • zp47 antibody
  • zp47pou antibody

Protein level used designations for POU3F2

POU domain, class 3, transcription factor 2 , brain-2 , brain-specific homeobox/POU domain protein 2 , nervous system-specific octamer-binding transcription factor N-Oct-3 , octamer-binding protein 7 , octamer-binding transcription factor 7 , POU domain, class 3, transcription factor 2-B , POU domain, class 3, transcription factor 4 , transcription factor POU3-B , xlPOU3B , brain-2 class III POU-domain protein , POU domain, class 3, transcription factor 2-A , transcription factor POU3-A , xlPOU3A , protein Brn-2 , POU class 3 homeobox 2 , POU domain gene 47 , POU domain protein 47 , POU domain protein ZP-47 , ZP-47 , LOW QUALITY PROTEIN: POU domain, class 3, transcription factor 2 , POU class 3 homeobox 2a , brain POU domain gene 1.2

GENE ID SPECIES
5454 Homo sapiens
779122 Xenopus laevis
18992 Mus musculus
394422 Xenopus laevis
29588 Rattus norvegicus
30397 Danio rerio
481931 Canis lupus familiaris
783320 Bos taurus
100157279 Sus scrofa
106027148 Cavia porcellus
30547 Danio rerio
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