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PAX7 is a member of the paired box (PAX) family of transcription factors. Additionally we are shipping PAX7 Kits (4) and PAX7 Proteins (4) and many more products for this protein.
Showing 10 out of 264 products:
Cow (Bovine) Polyclonal PAX7 Primary Antibody for IHC, WB - ABIN2777560
Akahori, Karmali, Polavarapu, Lyle, Weiss, Shin, Husain, Naqvi, Van Dam, Habib, Choi, King, Pachura, Taylor, Lefer, Finn: CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury. in Nature communications 2015
Show all 6 Pubmed References
Human Polyclonal PAX7 Primary Antibody for FACS, IF (p) - ABIN739905
Oh, Lee, Lee, Oh, Lim, Ahn, Hwang, Kang: Functional and histological evidence for the targeted therapy using biocompatible polycaprolactone beads and autologous myoblasts in a dog model of fecal incontinence. in Diseases of the colon and rectum 2015
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Bat Polyclonal PAX7 Primary Antibody for WB - ABIN610569
Ku, Meier: Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells. in The Journal of biological chemistry 2000
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Cow (Bovine) Polyclonal PAX7 Primary Antibody for IF, WB - ABIN2777185
Ezin, Sechrist, Zah, Bronner, Fraser: Early regulative ability of the neuroepithelium to form cardiac neural crest. in Developmental biology 2011
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Mouse (Murine) Monoclonal PAX7 Primary Antibody for ICC, IF - ABIN2668735
Harada, Okada, Saiwai, Aoki, Nakamura, Ohkawa: Generation of a rat monoclonal antibody specific for Pax7. in Hybridoma (2005) 2009
Human Polyclonal PAX7 Primary Antibody for FACS - ABIN4912793
Sente, Van Berendoncks, Jonckheere, Rodenburg, Lauwers, Van Hoof, Wouters, Lardon, Hoymans, Vrints: Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity. in BMC cardiovascular disorders 2016
Cow (Bovine) Polyclonal PAX7 Primary Antibody for IHC, WB - ABIN2779615
Du, Lawrence, Strzelecki, Rajput, Xia, Gottesman, Barr: Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma. in International journal of cancer. Journal international du cancer 2005
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These data suggested that expression of the myogenic regulatory transcription factors are dependent upon expression of glypican-1 (show GPC1 Antibodies) and syndecan-4 (show SDC4 Antibodies) during satellite cell proliferation and differentiation, and Pax7 expression is influenced by glypican-1 (show GPC1 Antibodies).
Transfection experiments showed that the PAX7 splice-site mutation putatively causes nonsense-mediated mRNA decay affecting onlyPAX7 isoform 3.
The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain.
EWSR1 (show EWSR1 Antibodies) fusion protein is required for PAX7 expression in Ewing sarcoma and identify a candidate EWSR1 (show EWSR1 Antibodies)-FLI1 (show FLI1 Antibodies)-bound PAX7 enhancer that coincides with both a consensus GGAA repeat-containing binding site and a peak of regulatory H3K27 acetylation.
miR (show MLXIP Antibodies)-206 acts as a tumor suppressor in fusion-negative RMS at least partially through downregulation of PAX7.
PAX7 expression is a useful marker of skeletal muscle differentiation in rhabdomyosarcoma, particularly of the embryonal subtype, with specificity for rhabdomyosarcoma and Ewing sarcoma.
NTN1 (show NTN1 Antibodies) rs9788972 is identified as a risk locus for nonsyndromic orofacial clefts susceptibility in a northern Chinese population; SNPs in PAX7 were not associated with any increased risk
Our results on Pax7 and MyoD protein expression suggest that proliferation and differentiation of skeletal muscle stem cells are affected in ALS patients, and the myogenic processes cannot overcome the denervation-induced wasting.
these results suggest that sarcoma metastasis can be partially controlled through Pax7/MyoD (show MYOD1 Antibodies)-dependent activation of miR (show MLXIP Antibodies)-182 and provide insight into the role that myogenic transcription factors have in sarcoma progression
RAGE (show AGER Antibodies) upregulates myogenin (show MYOG Antibodies) which upregulates MyoD (show MYOD1 Antibodies) and downregulates PAX7, with consequent inhibition of proliferation and stimulation of differentiation.
Pax7 responds to NF-kappaB (show NFKB1 Antibodies) by impairing the regenerative capacity of myogenic cells in the muscle microenvironment to drive muscle wasting in cancer.
Our results show that the expression of Pax6 (show PAX6 Antibodies) and Pax7 is widely maintained in the adult brain of Xenopus
The Pax3 (show PAX3 Antibodies) and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos.
Results show that inhibition of pax7 does not prevent differentiation of satellite cells to myofibres, but it does prevent their maintenance as a stem cell population.
four novel polymorphisms were identified in the Pax7 gene; the association analysis of genotypes in the single and combined SNP(s) revealed consistent effects on growth traits in NY cattle
Pax7 activates Zac1 (show PLAGL1 Antibodies) to regulate GPR39 (show GPR39 Antibodies) expression in myocytes.
Barx2 (show BARX2 Antibodies) and Pax7 regulate the canonical Wnt (show WNT2 Antibodies) target gene Axin2 (show AXIN2 Antibodies), which mediates critical feedback to terminate the transcriptional response to Wnt (show WNT2 Antibodies) signals.
Stat3 (show STAT3 Antibodies) regulates self-renewal of adult muscle satellite cells during injury-induced muscle regeneration through various partners, such as Pax7.
Lkb1 (show STK11 Antibodies) activates the Notch (show NOTCH1 Antibodies) signaling pathway, which subsequently increases Pax7 expression and promotes self-renewal and proliferation while inhibiting differentiation. Mechanistic studies reveal that Lkb1 (show STK11 Antibodies) regulates Notch (show NOTCH1 Antibodies) activation through AMPK (show PRKAA1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway in myoblasts.
Pax7 binding induces dramatic, localized remodeling of chromatin characterized by the acquisition of histone marks associated with enhancer activity and induction of chromatin accessibility in both muscle precursors and lineage-committed myoblasts. Conversely, removal of Pax7 leads to rapid reversal of these features on a subset of enhancers.
the absence of functional Pax7 in differentiating embryonic stem cells modulates cell cycle facilitating their proliferation.
findings demonstrate a key role for the lingual epithelial signals in supporting the integrity of the lamina propria and muscular tissue during tongue development and that a Wnt (show WNT2 Antibodies)/Notch (show NOTCH1 Antibodies)/Pax7 genetic hierarchy is involved in this development.
results support the concept that lack of functional Pax7 promotes proliferation of differentiating ESCs (show NR2E3 Antibodies) and for this reason more of them can turn into myogenic lineage.
Cells marked by pax7a only or by both pax7a and pax7b enter the wound rapidly and contribute to muscle wound repair, but each behaves differently.
Pax7 is required for adult skeletal muscle repair.
Pax7 identifies neural crest, chromatophore lineages and pigment stem cells during development.
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
paired box 7
, paired box gene 7
, transcription factor pax-7
, PAX7 transcriptional factor
, paired box homeotic gene 7
, paired box protein Pax-7
, paired domain gene 7
, myogenic specification paired-box transcription factor Pax7
, paired box transcription factor PAX7
, paired box homeotic gene 7a
, paired box homeotic gene 7c
, paired box homeotic gene 7d
, paired box homeotic gene 7e