PILRA Proteins

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes.

Data Quality
  • 5
Type
  • 9
    Protein
Antigen
  • 9
Reactivity
  • 6
  • 3
Application
  • 8
  • 5
  • 5
  • 4
  • 1
Host
  • 4
  • 2
  • 2
  • 1
Binding Specificity
  • 4
  • 1
  • 1
  • 1
  • 1
Conjugate
  • 1
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  • 2
  • 1
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Protein Type
  • 9
Format
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Biological Activity
  • 1
9 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3121716
$5,122.60
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3086057
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3121715
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3086056
$7,294.44
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315094
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Human Cells (Source), Purity (85.2+13.3) % as determined by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2005904
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Human Cells (Source), Purity > 95 % as determined by SDS-PAGE.
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2005906
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Human Cells (Source), Purity > 85 % as determined by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2005908
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Human Cells (Source), Purity > 97 % as determined by SDS-PAGE
ReactivityMouse (Murine)
Application Func, SDS
Order details Cat. No. ABIN2007549
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
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PILRA Protein Profile

Protein Summary

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.

Gene names and symbols associated with PILRA

  • paired immunoglobin like type 2 receptor alpha (PILRA) antibody
  • paired immunoglobulin-like type 2 receptor alpha (LOC489841) antibody
  • paired immunoglobin-like type 2 receptor alpha (Pilra) antibody
  • AV021745 antibody
  • FDF03 antibody
  • PILRA antibody
  • RGD1562847 antibody

Protein level used designations for PILRA

paired immunoglobulin-like type 2 receptor alpha , paired immunoglobin-like type 2 receptor alpha , cell surface receptor FDF03 , inhibitory receptor PILR-alpha

GENE ID SPECIES
463597 Pan troglodytes
489841 Canis lupus familiaris
100137734 Bos taurus
29992 Homo sapiens
231805 Mus musculus
288568 Rattus norvegicus