PILRA Proteins
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes.
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Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 32-302) protein (rho-1D4 tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 20-197) protein (His tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 32-198) protein (His tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 20-303) protein (rho-1D4 tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 1-226) protein (GST tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 1-197), (Extracellular Domain) (Active) protein (His tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 1-226) protein (His tag) Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 1-226) Protein Protein
Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) (AA 1-226) protein (Fc Tag) Protein
PILRA Protein Profile
Protein Summary
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.
Gene names and symbols associated with PILRA
- paired immunoglobin like type 2 receptor alpha (PILRA) antibody
- paired immunoglobulin-like type 2 receptor alpha (LOC489841) antibody
- paired immunoglobin-like type 2 receptor alpha (Pilra) antibody
- AV021745 antibody
- FDF03 antibody
- PILRA antibody
- RGD1562847 antibody
Protein level used designations for PILRA
paired immunoglobulin-like type 2 receptor alpha , paired immunoglobin-like type 2 receptor alpha , cell surface receptor FDF03 , inhibitory receptor PILR-alpha
GENE ID | SPECIES |
---|---|
463597 | Pan troglodytes |
489841 | Canis lupus familiaris |
100137734 | Bos taurus |
29992 | Homo sapiens |
231805 | Mus musculus |
288568 | Rattus norvegicus |
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