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The DNA-associated protein encoded by PRRX1 is a member of the paired family of homeobox proteins localized to the nucleus. Additionally we are shipping PRRX1 Antibodies (105) and PRRX1 Proteins (9) and many more products for this protein.
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Low PRRX1 expression is associated with hepatocellular carcinoma.
identified a functional genetic variant that alters PRRX1 expression, ultimately resulting in electrophysiological alterations in atrial myocytes that may promote Atrial fibrillation.
The glioma-initiating cells self-renewal function regulated by PRRX1 is mediated by dopamine D2 receptor (DRD2 (show DRD2 ELISA Kits)). PRRX1 directly binds to the DRD2 (show DRD2 ELISA Kits) promoter and transactivates its expression in glioma-initiating cells.
LGR5 (show LGR5 ELISA Kits)-expressing fraction of CD54 (show ICAM1 ELISA Kits)+ cells represents gastric cancer CSCs, in which LGR5 (show LGR5 ELISA Kits) is closely associated with stemness and EMT (show ITK ELISA Kits) core genes
miR (show MLXIP ELISA Kits)-655 inhibits the acquisition of the epithelial-mesenchymal transition phenotype in triple-negative breast cancer by down-regulating Prrx1, thereby inhibiting cell migration and invasion during cancer progression.
Decreased Expression of PRRX1 was Associated with Hepatocellular Carcinoma.
the switch from Prrx1b to Prrx1a governs EMT (show ITK ELISA Kits) plasticity in both mouse models of PDAC and human PDAC
These findings demonstrate that PRRX1 promotes epithelial-mesenchymal transition in gastric cancer cells
Our results indicate that activation of Notch (show NOTCH1 ELISA Kits) signaling by PRRX1 is associated with the promotion of glioblastoma cell invasion.
We conclude that miR (show MLXIP ELISA Kits)-146b-5p has a role in cell proliferation and invasion, and that PRRX1 plays an important role in papillary thyroid carcinoma epithelial-mesenchymal transition and disease progression.
Postnatal PRX1 (show PRDX1 ELISA Kits)-expressing stem cells of the calvaria are required for bone regeneration.
Data show that p38alpha (show MAPK14 ELISA Kits) mitogen-activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) in paired related homeobox 1 protein (Prx1 (show PRDX1 ELISA Kits)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG (show TNFRSF11B ELISA Kits)) production.
These data suggest the presence of a novel oxidative-stress-handling pathway where the anti-p53 (show TP53 ELISA Kits) molecule fortilin (show TPT1 ELISA Kits) augments the peroxidase PRX1 (show PRDX1 ELISA Kits) by protecting it against degradation and inactivation of the enzyme.
Induction of Prx1 (show PRDX1 ELISA Kits) by hypoxia regulates heme oxygenase-1 (show HMOX1 ELISA Kits) via NF-kappaB (show NFKB1 ELISA Kits) in oral cancer.
PRX-1 has a regulatory role in NF-kappaB (show NFKB1 ELISA Kits) nuclear translocation.
The data of this study suggested that Prx1 (show PRDX1 ELISA Kits) plays an important role as a key switch for neural cell lineage determination and the maintenance of the self-renewal of adult NSCs at several stages in the adult brain.
These observations suggest that increased Prrx1 expression may promote TGFbeta (show TGFB1 ELISA Kits) activity in adipose tissue and thereby contribute to aberrant adipocyte function during obesity.
The two isoforms, Prrx1a and Prrx1b, regulate migration and invasion, respectively, in pancreatic cancer cells
The results suggested that scarless skin-wound healing may require activation of the prx1 (show PRDX1 ELISA Kits) limb enhancer, and competence to activate the enhancer is probably a prerequisite for epimorphic regeneration, such as limb regeneration.
These results identify the homeobox protein (show HOXA1 ELISA Kits) Prx1 (show PRDX1 ELISA Kits) as an obligate mediator of TNF (show TNF ELISA Kits) inhibition of Osx (show SP7 ELISA Kits) and differentiation of osteoblast progenitors.
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.
homeobox protein PHOX1
, paired mesoderm homeo box 1
, paired mesoderm homeobox 1 isoform pmx-1b
, paired mesoderm homeobox protein 1
, paired-related homeobox protein 1
, homeobox protein K-2
, homeobox protein mHox
, paired mesoderm homeobox 1
, homeobox protein MHOX
, paired-related homeotic gene product
, paired related homeobox 1
, LOW QUALITY PROTEIN: paired mesoderm homeobox protein 1