anti-Paired-Like Homeodomain 1 (PITX1) Antibodies

PITX1 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins.

list all antibodies Gene Name GeneID UniProt
Anti-Human PITX1 PITX1 5307 P78337
Anti-Rat PITX1 PITX1 113983 Q99NA7
Anti-Mouse PITX1 PITX1 18740 P70314
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Top anti-PITX1 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PITX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  MCF7 cell lysate Host:  Rabbit  Target Name:  PITX1  Sample Type:  Human Hela  Antibody Dilution:  1.0ug/ml  PITX1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Pitx1 Antibody   Titration: 1.0 ug/ml   Positive Control: Rat Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PITX1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  Jurkat cell lysate WB Suggested Anti-PITX1 <br /> Antibody Titration: 1.25 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat/COLO cells, using PITX1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PITX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate WB Suggested Anti-PITX1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: PITX1 Antibody [NBP1-88644] - Staining of human cell line U-2 OS shows positivity in nucleoli. Antibody staining is shown in green. Immunohistochemistry-Paraffin: PITX1 Antibody [NBP1-88644] - Immunohistochemical staining of human esophagus shows strong nuclesr positivity in squamous epithelial cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PITX1 antibody (Center) (ABIN391506) in NCI-H460 cell line lysates (35 µg/lane). PITX1 (arrow) was detected using the purified polyclonal antibody. PITX1 Antibody (Center) (ABIN391506) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IP, RNAi, ELISA, WB PITX1 monoclonal antibody (M01), clone 5G4 Western Blot analysis of PITX1 expression in Hela S3 NE . Western blot analysis of PITX1 over-expressed 293 cell line, cotransfected with PITX1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with PITX1 monoclonal antibody (M01), clone 5G4. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 11 to 12 Days
$440.00
Details

Top referenced anti-PITX1 Antibodies

  1. Human Monoclonal PITX1 Primary Antibody for IP, RNAi - ABIN562248 : Liu, Lobie: Transcriptional activation of p53 by Pitx1. in Cell death and differentiation 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PITX1 Primary Antibody for IF, WB - ABIN518913 : Mullen, Park, Rhodes: A distal modular enhancer complex acts to control pituitary- and nervous system-specific expression of the LHX3 regulatory gene. in Molecular endocrinology (Baltimore, Md.) 2012 (PubMed)

  3. Human Monoclonal PITX1 Primary Antibody for ELISA, WB - ABIN518914 : Yamaguchi, Miki, Yoshida: The c-Abl tyrosine kinase stabilizes Pitx1 in the apoptotic response to DNA damage. in Apoptosis : an international journal on programmed cell death 2010 (PubMed)

  4. Human Polyclonal PITX1 Primary Antibody for IP, WB - ABIN151090 : Stender, Stossi, Funk, Charn, Barnett, Katzenellenbogen: The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells. in Molecular endocrinology (Baltimore, Md.) 2011 (PubMed)

  5. Human Polyclonal PITX1 Primary Antibody for ICC, IF - ABIN4345764 : Boumahdi, Driessens, Lapouge, Rorive, Nassar, Le Mercier, Delatte, Caauwe, Lenglez, Nkusi, Brohée, Salmon, Dubois, del Marmol, Fuks, Beck, Blanpain: SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma. in Nature 2014 (PubMed)

More Antibodies against PITX1 Interaction Partners

Human Paired-Like Homeodomain 1 (PITX1) interaction partners

  1. we demonstrated a novel oncogenic mechanism of PTP1B (show PTPN1 Antibodies) on affecting PITX1/p120RasGAP (show RASA1 Antibodies) in colorectal carcinoma(CRC (show CALR Antibodies)). Regorafenib inhibited CRC (show CALR Antibodies) survival through reserving PTP1B (show PTPN1 Antibodies)-dependant PITX1/p120RasGAP (show RASA1 Antibodies) downregulation. PTP1B (show PTPN1 Antibodies) may be a potential biomarker predicting regorafenib effectiveness, and a potential solution for CRC (show CALR Antibodies)

  2. Methylation status of PITX1 and even more so of lincRNA C5orf66-AS1 is a promising prognostic biomarker in HNSCC, in particular for HPV-negative patients. Further prospective evaluation is warranted

  3. role for E2F1 (show E2F1 Antibodies) and TFDP1 (show TFDP1 Antibodies) in the transcriptional regulation of PITX1 in articular chondrocytes

  4. PITX1 expression may be involved in tumor progression and is a potential tumor suppressor gene and prognostic marker for cutaneous malignant melanoma.

  5. PTP1B (show PTPN1 Antibodies) dephosphorylates PITX1 to weaken its protein stability and the transcriptional activity for p120RasGAP (show RASA1 Antibodies) gene expression

  6. To date, at least ten loci and four non-syndromic polydactyly-causing genes, including the GLI3 (show GLI3 Antibodies) gene, the ZNF141 (show ZNF141 Antibodies) gene, the MIPOL1 (show MIPOL1 Antibodies) gene and the PITX1 gene, have been identified. (Review)

  7. Low PITX1 expression is associated with lung metastasis in osteosarcoma.

  8. We discuss the genetic abnormality that causes Liebenberg syndrome, the genomic rearrangement at the PITX1 locus on chromosome 5.

  9. Down-regulation of PITX1 expression might contribute to the progression of cutaneous malignant melanoma via promoting cell proliferative activity

  10. PITX1 regulates HIF-1a (show HIF1A Antibodies) activity by binding to HIF-1b and regulatingHIF recruitment to specific target promoters.

Mouse (Murine) Paired-Like Homeodomain 1 (PITX1) interaction partners

  1. Pitx1 distal enhancer loss have only mild effects on Pitx1 expression in the hindlimb and no overt effects on hindlimb or mandibular morphology.

  2. data suggest that PITX1 promotes chondrogenesis and myogenesis in the hindlimb by direct regulation of several key members of the cartilage and muscle transcriptional networks.

  3. Results indicate autonomously programmed differences in forelimb and hindlimb cartilage precursors of the limb skeleton are controlled, at least in part, by Pitx1 and suggest this has an important role in generating distinct limb-type morphologies.

  4. Pitx1 targets sites that are in a similar chromatin state in Forelimbs (FLs) and hindlimbs and controls expression of patterning genes as well as the chondrogenic program.

  5. Pitx1 influences hindlimb morphology both through the activation of hindlimb-specific enhancers as well as through the hindlimb-specific modulation of enhancers that are active in both sets of limbs

  6. The results suggest that PITX2 (show PITX2 Antibodies) and PITX1 have overlapping roles in thyrotroph function and response to hypothyroidism.

  7. PITX1 haploinsufficiency may cause a developmental field defect preferentially affecting the lateral lower leg.

  8. It was shown that, firstly, Pitx1 influences hindlimb outgrowth by regulating Tbx4 (show TBX4 Antibodies) expression levels and that, subsequently,Pitx1 shapes hindlimb bone and soft tissue morphology independently of Tbx4 (show TBX4 Antibodies).

  9. These findings provide evidence that c-Abl (show ABL1 Antibodies) participates in modulating Pitx1 expression in the apoptotic response to DNA damage.

  10. Thus, Pitx1 and Pitx2 (show PITX2 Antibodies) genes are required for sustained hindlimb bud growth and formation of hindlimbs

Xenopus laevis Paired-Like Homeodomain 1 (PITX1) interaction partners

  1. Pitx1 and the related protein Pitx2c (show PITX2 Antibodies) are required for endogenous cement gland development. Pitx1 transcriptionally activates cement gland differentiation genes, both directly and indirectly

  2. Pitx1 is expressed in hindlimbs and expression is similar in both developing and regenerating limb buds.

PITX1 Antigen Profile

Protein Summary

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

Gene names and symbols associated with PITX1

  • paired like homeodomain 1 (PITX1) antibody
  • paired like homeodomain 1 (pitx1) antibody
  • paired like homeodomain 2 (PITX2) antibody
  • paired-like homeodomain 1 (Pitx1) antibody
  • paired-like homeodomain 1 (pitx1) antibody
  • paired-like homeodomain transcription factor 1 (Pitx1) antibody
  • Pitx1 protein (pitx1) antibody
  • Bft antibody
  • CCF antibody
  • LBNBG antibody
  • MGC79589 antibody
  • P-OTX antibody
  • PITX1 antibody
  • Potx antibody
  • Ptx1 antibody
  • X-PITX-1 antibody
  • xPitx1 antibody
  • zgc:136976 antibody

Protein level used designations for PITX1

paired-like homeodomain 1 , paired-like homeodomain transcription factor 1 , pituitary homeobox 1 , Pitx2 , hindlimb expressed homeobox protein backfoot , hindlimb-expressed homeobox protein backfoot , homeobox protein PITX1 , pituitary homeo box 1 , pituitary otx-related factor , cPTX1 , homeobox protein P-OTX , pituitary OTX-related factor , xPitx1

GENE ID SPECIES
462072 Pan troglodytes
493226 Xenopus (Silurana) tropicalis
508754 Bos taurus
100009361 Oryctolagus cuniculus
5307 Homo sapiens
374201 Gallus gallus
481513 Canis lupus familiaris
113983 Rattus norvegicus
678598 Danio rerio
18740 Mus musculus
398122 Xenopus laevis
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