Pannexin 1 (PANX1) ELISA Kits

The protein encoded by PANX1 belongs to the innexin family. Additionally we are shipping Pannexin 1 Antibodies (63) and Pannexin 1 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PANX1 24145 Q96RD7
PANX1 55991 Q9JIP4
PANX1 315435 P60570
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Top Pannexin 1 ELISA Kits at

Showing 4 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.064 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Rat < 0.092 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
  96 Tests Log in to see 11 to 18 Days
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  10 reactions Log in to see 4 to 6 Days

More ELISA Kits for Pannexin 1 Interaction Partners

Zebrafish Pannexin 1 (PANX1) interaction partners

  1. Extracellular ATP hydrolysis via NTPDase1 action inhibits synaptic transmission by pannexin 1-mediated increase in pH buffering of the synaptic cleft.

  2. The existence of two Panx1 proteins in zebrafish displaying distinct tissue distribution, protein modification and electrophysiological properties, suggests that both proteins fulfill different functions in vivo.

  3. The function of panx1 channel is significantly reduced following mutation of a single cysteine residue (C282W) in the fourth transmembrane region of panx1.

  4. zfPanx1 displays properties similar to its mammalian homologues and can potentially play an important role in functions of the outer retina.

Human Pannexin 1 (PANX1) interaction partners

  1. Progressive PANX1 channel opening is directly linked to permeation of ions and large and occurs during both irreversible and reversible forms of channel activation. This unique, quantized activation process enables fine tuning of PANX1 channel activity and may be a generalized regulatory mechanism for other related multimeric channels.

  2. authors proposed a tentative intracellular signaling pathway of the acetylcholine-induced ciliary beat, in which the pannexin-1-purinergic P2X receptor unit may play a central role in ciliary beat regulation

  3. These results newly identify Pannexin-1 as a protein highly expressed in human dermal lymphatic endothelial cells.

  4. The pannexin 2 (Panx2) N86Q mutant is glycosylation-deficient and tends to aggregate in the endoplasmic reticulum (ER)reducing its cell surface trafficking but it can still interact with pannexin 1 (Panx1).

  5. All three pannexins Panx1, Panx2, and Panx3 mRNAs were expressed in all of the analyzed undifferentiated stem cell lines.

  6. These results elucidate for the first time PNX1-hemichannels as potentially main extracellular translocation pathway for NDKs from an intracellular pathogen.

  7. Pannexin1 (Panx1) was suggested to be functionally associated with purinergic P2X and N-methyl-D-aspartate (NMDA) receptor channels. Activation of these receptor channels by their endogenous ligands leads to cross-activation of Panx1 channels. This in turn potentiates P2X and NMDA receptor channel signaling.

  8. The ubiquitous expression, as well as its function as a major ATP release and nucleotide permeation channel, makes Panx1 a primary candidate for participating in the pathophysiology of CNS disorders.

  9. Panx1 was mainly distributed in microcolumn neurons, dysmorphic neurons, balloon cells and reactive astrocytes in cortical lesions from intractable epilepsy patients with focal cortical dysplasia.

  10. ATP release from red blood cells is not mediated by the cAMP-mediated Panx1 pathway.

  11. Panx1 channels are involved in beta-toxin-induced cell death.

  12. Pannexin1 is a mediator of inflammation and cell death. (Review)

  13. Panx1 channels promote skeletal muscle myoblast differentiation and fusion. (Review)

  14. presence of the Panx1-400C allele was not associated with platelet reactivity in stable cardiovascular patients.

  15. Overactive Panx-1 promotes cancer cell survival in the context of mechanical deformation. Panx-1 inhibitors can be used to treat highly metastatic cancer. Mechanosensitive Panx-1 channels will be a new target for the prevention of metastasis and stress-induced diseases.

  16. The results of this study do not support a major contribution of PANX1-3 to disease risk of schizophrenia according to DSM-5.

  17. a pivotal role of P2X7 receptor-pannexin-1 in oxysterols toxicity in retinal cells

  18. Data indicate that the consanguineous parents are each heterozygous for Pannexin1 (PANX1) but are not affected by the multiorgan syndromes.

  19. CBX and other inhibitors, including probenecid, attenuate Panx1 channel activity through modulation of the first extracellular loop.

  20. Decreased Panx1 function is a response to cell acidification mediated by IFN-gamma-induced up-regulation of Duox2.

Mouse (Murine) Pannexin 1 (PANX1) interaction partners

  1. Panx1 expressed in immune cells is critical for pain-like effects following nerve injury in mice, perhaps via a GPCR-mediated activation mechanism, and suggest that inhibition of Panx1 may be useful in treating neuropathic pain.

  2. Auditory brainstem response thresholds in the Gen-Panx1 KO mouse were significantly increased. Distortion product otoacoustic emission and cochlear microphonics were significantly reduced.

  3. These novel findings reveal unique roles for GFAP-positive glial and neuronal Panx1 and describe new chronic pain targets for cell-type specific intervention in this often intractable disease.

  4. Panx-1 modulation may be interesting to amplify the clinical effect of cisplatin (DDP) and reverse the resistance of testicular cancer cells to DDP.

  5. Pannexin1 may play a role in the pathogenesis of liver disease.

  6. Findings indicate a deleterious role for membrane channel Pannexin 1 (Panx1) in response to permanent permanent middle cerebral artery (MCA) occlusion, that is unique to females.

  7. ATP release from red blood cells is not mediated by the cAMP-mediated Panx1 pathway.

  8. blocking Panx1 and/or Casp4 activities is a beneficial strategy to enhance donor cell engraftment and LG regeneration through the reduction of inflammation.

  9. found a significant increase in waking and a correspondent decrease in slow wave sleep percentages in the Panx1-/- animals.

  10. Diabetic C57BL/6J-Ins2Akita mice were used to evaluate in vivo effects of high glucose on P2R and Panx1

  11. Pharmacological blockade or genetic deletion of Panx1 channels inhibits CD4+ T lymphocyte polarization and migration induced by the chemokine SDF-1alpha/CXCL12. Panx1 deficiency delayed experimental autoimmune encephalomyelitis symptoms because of the decreased infiltration of CD4+ T lymphocytes into the CNS.

  12. data suggest that Panx1 and Panx3 are not essential for baseline hearing in mice tested, but the therapeutic targeting of Panx3 may prove protective against mid-high-frequency hearing loss caused by loud NE.

  13. Pannexin1 (Panx1) is dynamically regulated throughout mammary gland development.

  14. These results indicate that activation of Panx1 and P2X7 R are required for apoptotic osteocytes in fatigued bone to trigger RANKL production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.

  15. Panx1 is expressed in the central and peripheral nervous system during early developmental stages.

  16. this study provides the first demonstration of Panx1 channel morphology and assembly in intact cells.

  17. Panx1 in the heart influences different electrophysiological parameters involving depolarization, repolarization and atrial vulnerability causing atrial fibrillation.

  18. ATP released by myocardial cells through Pannexin-1 channel during ischemia could evoke calcium responses in cardiac sympathetic nerve fibers.

  19. Platelets of Panx1-/- mice showed reduced collagen-induced aggregation as compared to those of WT mice.

  20. The observations of this study reveal a new role for Panx1 in NPC maintenance in the VZ and suggesting that targeting peri-infarct Panx1 (in combination with other interventions) could improve outcomes after stroke.

Pannexin 1 (PANX1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Gene names and symbols associated with Pannexin 1 (PANX1) ELISA Kits

  • pannexin 1a (panx1a) antibody
  • pannexin 1 (PANX1) antibody
  • pannexin 1 (panx1) antibody
  • pannexin 1 (Panx1) antibody
  • Pannexin 1 (Panx1) antibody
  • AI847747 antibody
  • MRS1 antibody
  • Pannexin-1 antibody
  • pannexin1 antibody
  • PANX1 antibody
  • PX1 antibody
  • UNQ2529 antibody
  • zgc:55631 antibody

Protein level used designations for Pannexin 1 (PANX1) ELISA Kits

pannexin 1 , pannexin-1 , innexin

393890 Danio rerio
466751 Pan troglodytes
697204 Macaca mulatta
772164 Gallus gallus
100014304 Monodelphis domestica
100170473 Xenopus (Silurana) tropicalis
100171730 Pongo abelii
24145 Homo sapiens
607532 Canis lupus familiaris
528169 Bos taurus
55991 Mus musculus
315435 Rattus norvegicus
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