anti-Parvin, beta (PARVB) Antibodies

PARVB encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. Additionally we are shipping Parvin, beta Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PARVB 29780 Q9HBI1
PARVB 170736 Q9ES46
PARVB 362973  
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Top anti-Parvin, beta Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PARVB Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Liver 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PARVB Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Transfected 293T 100 μL 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated IHC, WB ABIN6273287 at 1/100 staining Human pancreas cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of mouse spleen tissue, using PARVB antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using PARVB antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of PARVB expression in transfected 293T cell line by PARVB monoclonal antibody (M01), clone 4A11.Lane 1: PARVB transfected lysate(40.25 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged PARVB is 1 ng/ml as a capture antibody. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB PARVB antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details

Top referenced anti-Parvin, beta Antibodies

  1. Human Monoclonal PARVB Primary Antibody for ELISA, WB - ABIN565418 : Wu, Ng, Chen, Chang, Chuang, Weng, Liao, Pang: Expression of parvin-beta is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract. in British journal of cancer 2010 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Parvin, beta Interaction Partners

Human Parvin, beta (PARVB) interaction partners

  1. Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with non-alcoholic fatty liver disease.

  2. Protein expression of beta-Parvin increases with colorectal cancer progression.

  3. Taken together, our results indicate that 24-MCF treatment increases parvin-beta expression, which may inhibit ILK downstream signaling.

  4. study found polymorphisms of rs5764455 and rs6006473 in PARVB gene in the Han Chinese population, and these polymorphisms were associated with the occurrence and progression of NAFLD.

  5. Our results suggested that variations, including insertion/deletions, in PARVB, as well as those in PNPLA3, are important in the progression of NAFLD.

  6. PARVB overexpression is a candidate biomarker for endophytic tumours and metastasis.

  7. PARVB plays a potential role in the pathogenesis of coronary restenosis.

  8. Polymorphisms in the SAMM50 and PARVB genes in addition to those in the PNPLA3 gene were observed to be associated with the development and progression of NAFLD.

  9. alpha-parvin, beta-parvin and migfilin were expressed in tumor cells in 53%, 2%, 28% and 53% of effusions and 57%, 20%, 83% and 25% of solid lesions, respectively.

  10. proper localization of beta-parvin to focal adhesions requires both the paxillin and integrin-linked kinase binding sites and that paxillin is important for early targeting of beta-parvin.

  11. Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.

  12. downexpression of ParvB level in urothelial cell carcinoma of the upper urinary tract (UUT-UC) correlated with tumour stage, and was an independent unfavourable prognostic factor for disease-specific survival of patients with UUT-UC

  13. Data from functional molecular imaging demonstrated that beta-parvin plays a regulatory role in the ILK-mediated Akt (also called protein kinase B) signaling cascades, suggesting that beta-parvin might be a crucial modulator of cell survival.

  14. Mammalian parvins are likely to have arisen late in evolution from gene duplication as they share a remarkably similar exon/intron organization.

  15. the ILK-affixin complex has a role in integrin-cytoskeleton linkage during platelet aggregation [affixin]

  16. affixin provide a novel signalling pathway that links integrin signalling to Cdc42/Rac1 activation.

  17. ILK-affixin complex serves as an integrin-anchoring site for alpha-actinin and thereby mediates integrin signaling to alpha-actinin, which has been shown to play a critical role in actin polymerization at focal adhesions.

  18. alpha- and beta-parvins play distinct roles in Rac activation or lamellipodium formation and protection of cells from apoptosis.

  19. loss of ParvB expression is a novel mechanism for upregulating ILK activity in tumors

  20. Data show that affixin is a dysferlin binding protein that colocalizes with dysferlin at the sarcolemma of normal skeletal muscle.

Mouse (Murine) Parvin, beta (PARVB) interaction partners

  1. Parvins are critical for the organization of endothelial cell-cell junctions, the establishment of endothelial apical-basal polarity, and the integrity of the basement membrane.

  2. Data from functional molecular imaging demonstrated that beta-parvin plays a regulatory role in the ILK-mediated Akt (also called protein kinase B) signaling cascades, suggesting that beta-parvin might be a crucial modulator of cell survival.

  3. Data show that affixin is a dysferlin binding protein that colocalizes with dysferlin at the sarcolemma of normal skeletal muscle.

Parvin, beta (PARVB) Antigen Profile

Protein Summary

This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with anti-Parvin, beta (PARVB) Antibodies

  • parvin beta (parvb) antibody
  • parvin beta (PARVB) antibody
  • parvin, beta (parvb) antibody
  • parvin beta S homeolog (parvb.S) antibody
  • parvin, beta (Parvb) antibody
  • affixin antibody
  • AI595373 antibody
  • AW742462 antibody
  • beta-parvin antibody
  • CGI-56 antibody
  • D15Gsk1 antibody
  • fd02e01 antibody
  • wu:fd02e01 antibody
  • zgc:73117 antibody

Protein level used designations for anti-Parvin, beta (PARVB) Antibodies

parvin, beta , affixin , beta-parvin

GENE ID SPECIES
448070 Xenopus (Silurana) tropicalis
100011113 Monodelphis domestica
100556835 Anolis carolinensis
325686 Danio rerio
734573 Xenopus laevis
418235 Gallus gallus
29780 Homo sapiens
481215 Canis lupus familiaris
616294 Bos taurus
170736 Mus musculus
362973 Rattus norvegicus
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