Pepsinogen C Proteins (PGC)

PGC encodes an aspartic proteinase that belongs to the peptidase family A1. Additionally we are shipping PGC Antibodies (178) and PGC Kits (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PGC 5225 P20142
PGC 109820 Q9D7R7
PGC 24864 P04073
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Top PGC Proteins at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Human Cells Human His tag 10 μg Log in to see 14 to 16 Days
$250.80
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Human Cells Rat His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 13 to 16 Days
$1,230.77
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$448.00
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 11 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 8 to 11 Days
$341.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$720.00
Details

PGC Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus) , ,

More Proteins for Pepsinogen C (PGC) Interaction Partners

Human Pepsinogen C (PGC) interaction partners

  1. Recombinant pepsin C and pepsinogen C were purified from transgenic rice culture medium, and the NH2-terminal 5-residue sequences were verified by amino acid sequencing.

  2. Pepsinogen-II 100 bp ins (show INS Proteins)/del gene polymorphism and its elevated circulating levels are associated with gastric cancer, particularly with Helicobacter pylori infection and intestinal metaplasia.

  3. Results suggest that rs9471643 CG and rs6458238 AG/AA genotypes have important roles in up-regulating PGC expression, which may partially explain why individuals with these favorable genotypes have decreased risks of getting gastric cancer.

  4. Data show that SNP interactions among H. pylori-related genes PGC, PTPN11 (show PTPN11 Proteins), and IL1B (show IL1B Proteins), are associated with susceptibility to gastric carcinogenesis.

  5. Serum pepsinogens I (PGI (show BGN Proteins)) and II (PGII (show DCN Proteins)), gastrin (show GAST Proteins) 17 (G-17), and antibodies against whole H. pylori, or cytotoxin-associated gene A (CagA (show S100A8 Proteins)) antigen among 309 consecutive patients, were measured.

  6. The results highlight an important role of PGC rs3789210 and rs6939861 in altering susceptibility to atrophic gastritis and/or gastric cancer.

  7. Pepsinogen II is a good marker of corpus morphological changes before and after H. pylori eradication.

  8. High serum Pepsinogen II level is associ9ated with the progression of gastric precancerous lesions.

  9. An interaction effect of pri-let-7a-1 rs10739971 polymorphism with ERCC6 (show ERCC6 Proteins) rs1917799 polymorphism was observed for the risk of gastric cancer.

  10. Pepsin and pepsinogen in middle ear effusion are probably caused by LPR (show FAS Proteins) and may be involved in the pathogenesis of OME.

PGC Protein Profile

Protein Summary

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Gene names and symbols associated with Pepsinogen C Proteins (PGC)

  • progastricsin (pepsinogen C) (PGC)
  • progastricsin (PGC)
  • progastricsin (pepsinogen C) (Pgc)
  • progastricsin (Pgc)
  • 2210410L06Rik protein
  • CPGC protein
  • Gastricsin protein
  • PEPC protein
  • Pg-1 protein
  • PG1 protein
  • PGC protein
  • PGII protein
  • PGNC protein
  • Upg-1 protein
  • Upg1 protein

Protein level used designations for Pepsinogen C Proteins (PGC)

gastricsin , pepsinogen C , pepsin C , pepsinogen group II , preprogastricsin , urinary pepsinogen 1 , Urinary pepsinogen 1 , gastricsin-like

GENE ID SPECIES
554184 Monodelphis domestica
5225 Homo sapiens
109820 Mus musculus
395690 Gallus gallus
24864 Rattus norvegicus
100009323 Oryctolagus cuniculus
100135598 Cavia porcellus
100404738 Callithrix jacchus
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