PGC Proteins
PGC encodes an aspartic proteinase that belongs to the peptidase family A1.
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Pepsinogen C (PGC) (AA 60-388) protein (His tag) Protein
Pepsinogen C (PGC) (AA 63-392) protein (His tag) Protein
Pepsinogen C (PGC) (AA 61-388) protein (His tag) Protein
Pepsinogen C (PGC) (AA 1-388) protein (GST tag) Protein
Pepsinogen C (PGC) (AA 17-392) protein (GST tag,His tag) Protein
Pepsinogen C (PGC) (AA 17-392) protein (His tag) Protein
Pepsinogen C (PGC) protein (Myc-DYKDDDDK Tag) Protein
Pepsinogen C (PGC) Protein Protein
Pepsinogen C (PGC) Protein Protein
Pepsinogen C (PGC) (AA 17-388) protein (His tag) Protein
Pepsinogen C (PGC) (AA 1-388) protein (His tag) Protein
Pepsinogen C (PGC) (AA 1-392) protein (His tag) Protein
PGC Protein Profile
Protein Summary
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
Gene names and symbols associated with Pepsinogen C Proteins (PGC)
- progastricsin (pepsinogen C) (PGC) antibody
- progastricsin (PGC) antibody
- progastricsin (pepsinogen C) (Pgc) antibody
- progastricsin (Pgc) antibody
- 2210410L06Rik antibody
- CPGC antibody
- Gastricsin antibody
- PEPC antibody
- Pg-1 antibody
- PG1 antibody
- PGC antibody
- PGII antibody
- PGNC antibody
- Upg-1 antibody
- Upg1 antibody
Protein level used designations for Pepsinogen C Proteins (PGC)
gastricsin , pepsinogen C , pepsin C , pepsinogen group II , preprogastricsin , urinary pepsinogen 1 , Urinary pepsinogen 1 , gastricsin-like
GENE ID | SPECIES |
---|---|
554184 | Monodelphis domestica |
5225 | Homo sapiens |
109820 | Mus musculus |
395690 | Gallus gallus |
24864 | Rattus norvegicus |
100009323 | Oryctolagus cuniculus |
100135598 | Cavia porcellus |
100404738 | Callithrix jacchus |
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