anti-Peripheral Myelin Protein 22 (PMP22) Antibodies

PMP22 encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Additionally we are shipping PMP22 Kits (29) and PMP22 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PMP22 5376 Q01453
PMP22 18858 P16646
PMP22 24660 P25094
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Top anti-PMP22 Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PMP22 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of GAS3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of GAS3 expression in THP1 (A), MDAMB435 (B), mouse brain (C), mouse liver (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PMP22 Antibody  in Human normal Uterus cell line lysates (35ug/lane). This demonstrates the PMP22 antibody detected the PMP22 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from MDA-MB-435 cells, using PMP22 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PMP22 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IHC (p), IHC, WB Staining of PMP22 (brown) in dorsal root ganglion and spinal roots in 20 week fetal spinal cord preparation from rhesus monkey. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Rabbit Un-conjugated IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PMP22 antibody ABIN213869 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$561.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated (ABIN726680) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat spinal cord labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in human normal Uterus tissue lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

PMP22 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PMP22 Antibodies

  1. Monoclonal PMP22 Primary Antibody for IHC (p) - ABIN534026 : Gregson, Zhang, Pritchard, Wang, Sanvito, Hayday, Hughes: Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system. in Journal of the peripheral nervous system : JPNS 2007 (PubMed)

More Antibodies against PMP22 Interaction Partners

Human Peripheral Myelin Protein 22 (PMP22) interaction partners

  1. We identified that PMP22 not only acts as a marker for gastric CSCs but may also have an essential role in regulating the self-renewal and chemoresistance of gastric cancer. Our findings suggest that PMP22 has clinical value for the prognosis and treatment of chemoresistant gastric cancer

  2. In this Chinese Han population, the frequency of PMP22 gene duplication in those with CMT1 (show MPZ Antibodies) was slightly (50% vs. 70%-80%) less than in Western/Caucasian populations.

  3. PMP22 polymorphism is associated with tuberculosis.

  4. The studies implicating GAS3 protein family (EMP1, EMP2, EMP3 (show EMP3 Antibodies) and PMP22) in cancer pathogenesis as well as probe the structural similarities between the family members were highlighted.

  5. A Computational Approach to Identify a Potential Alternative Drug With Its Positive Impact Toward PMP22.

  6. Exome sequencing identified MFN2 (show MFN2 Antibodies) SNVs in two of the individuals. Neuropathy-associated CNV outside of the PMP22 locus is rare in Charcot-Marie-Tooth (CMT) disease . Nevertheless, there is potential clinical utility in testing for CNVs and exome sequencing in CMT cases negative for the CMT1A duplication.

  7. We discovered that Tead1 (show TEAD1 Antibodies) and co-activators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) are required for Pmp22 expression, as well as for the expression of Egr2 (show EGR2 Antibodies) Tead1 (show TEAD1 Antibodies) directly binds Pmp22 and Egr2 (show EGR2 Antibodies) enhancers early in development and Tead1 (show TEAD1 Antibodies) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (show TEAD1 Antibodies) as a novel regulator of Pmp22 expression during development in concert with Sox10 (show SOX10 Antibodies) and Egr2 (show EGR2 Antibodies)

  8. This study demonstrated We show that blink (show TGFb Antibodies) reflex studies are reliable for identification of inherited demyelinating polyneuropathy (with pmp22 mutation) regardless of severity and can facilitate algorithmic decisions in genetic testing.

  9. Findings suggest that miR (show MLXIP Antibodies)-200bc/429 inhibit OS cells proliferation and invasion by targeting PMP22, and function as a tumor suppressor.

  10. PMP22 deletion leads to functional, metabolic and macro-structural alterations in the afferent visual system of hereditary neuropathy with liability to pressure palsies patients.

Mouse (Murine) Peripheral Myelin Protein 22 (PMP22) interaction partners

  1. selective suppression of the Pmp22 mutant allele by non-viral delivery of siRNA alleviates the demyelinating neuropathic phenotypes of Charcot-Marie-Tooth disease in vivo

  2. We discovered that Tead1 (show TEAD1 Antibodies) and co-activators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) are required for Pmp22 expression, as well as for the expression of Egr2 (show EGR2 Antibodies) Tead1 (show TEAD1 Antibodies) directly binds Pmp22 and Egr2 (show EGR2 Antibodies) enhancers early in development and Tead1 (show TEAD1 Antibodies) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (show TEAD1 Antibodies) as a novel regulator of Pmp22 expression during development in concert with Sox10 (show SOX10 Antibodies) and Egr2 (show EGR2 Antibodies)

  3. The basal lamina and PMP22 act in concert to contribute to a resilience and integrity of peripheral nerves at the single fibre level.

  4. A role was identified for PMP22 in the linkage of the actin cytoskeleton with the plasma membrane.

  5. This study demonistrated that Paranodal dysmyelination in peripheral nerves of Trembler mice.

  6. This study showed that a number of ongoing pathogenic mechanisms contribute to the progression of the neuropathy in C22 mice, which initiates with abnormal expression of PMP22.

  7. This study revealed a novel mechanism by which PMP22 deficiency affects nerve conduction not through removal of myelin, but through disruption of myelin junctions

  8. This study showed that mouse PMP22 is palmitoylated at C85 and mutating C85S abolishes PMP22 palmitoylation.

  9. Peripheral myelin protein 22 (PMP22) performs distinct actions on the formation, maturation, degeneration and regeneration of sciatic nerve myelin sheath.

  10. Egr2 (show EGR2 Antibodies) and Sox10 (show SOX10 Antibodies) activity are directly involved in mediating the developmental induction of Pmp22 expression through an intronic enhancer.

Zebrafish Peripheral Myelin Protein 22 (PMP22) interaction partners

  1. The results of this study indicated that an adequate pmp22 transcription level is necessary for correct myelination of jawed vertebrates.

PMP22 Antigen Profile

Protein Summary

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.

Gene names and symbols associated with PMP22

  • peripheral myelin protein 22 (PMP22) antibody
  • peripheral myelin protein 22 (Pmp22) antibody
  • peripheral myelin protein 22a (pmp22a) antibody
  • peripheral myelin protein 22 S homeolog (pmp22.S) antibody
  • peripheral myelin protein 22 (pmp22) antibody
  • 22kDa antibody
  • CMT1A antibody
  • CMT1E antibody
  • DSS antibody
  • Gas-3 antibody
  • HMSNIA antibody
  • HNPP antibody
  • MGC69407 antibody
  • MGC80653 antibody
  • PMP22 antibody
  • Sp110 antibody
  • Tr antibody
  • trembler antibody
  • wu:fa04d03 antibody
  • wu:fa08d03 antibody

Protein level used designations for PMP22

growth arrest-specific protein 3 , PMP-22 , peripheral myelin protein, 22 kDa , SAG , SR13 myelin protein , schwann cell membrane glycoprotein , peripheral myelin protein 22 , PAS positive glycoprotein , PASII

GENE ID SPECIES
5376 Homo sapiens
18858 Mus musculus
24660 Rattus norvegicus
334817 Danio rerio
417327 Gallus gallus
446837 Xenopus laevis
479509 Canis lupus familiaris
534497 Bos taurus
594946 Xenopus (Silurana) tropicalis
693527 Macaca mulatta
744977 Pan troglodytes
100034146 Equus caballus
100172535 Pongo abelii
100302348 Ovis aries
100723804 Cavia porcellus
Selected quality suppliers for anti-PMP22 (PMP22) Antibodies
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