PMP22 antibody (AA 111-160)

Catalog No. ABIN1533382

The Rabbit Polyclonal anti-PMP22 antibody is suitable to detect PMP22 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for PMP22 antibody (AA 111-160) (ABIN1533382)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMP22 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PMP22 Antibody

Binding Specificity: AA 111-160

Purpose: GAS3 Antibody

Specificity: GAS3 Polyclonal Antibody detects endogenous levels of GAS3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PMP22. AA range:111-160

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Alternative Name: PMP22

Background:

Synonyms: PMP22, GAS3, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3

Background: This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Gene Name: PMP22

Protein Name: Peripheral myelin protein 22

Molecular Weight: 17 kDa

Gene ID: 5376

OMIM: 601097

UniProt: Q01453