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anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Antibodies

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005. Additionally we are shipping Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PITPNM1 18739 O35954
PITPNM1 9600 O00562
PITPNM1 361694 Q5U2N3
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Top anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PITPNM1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart WB Suggested Anti-PITPNM1 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Goat Un-conjugated ELISA, ICC, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated WB Western Blot: NIR2 Antibody [NBP1-69043] - Human Heart lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB PITPNM1 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PITPNM1 antibody detected the PITPNM1 protein (arrow). PITPNM1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the PITPNM1 antibody detected the PITPNM1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Goat Un-conjugated IF, WB   0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry: NIR2 Antibody [NBP2-34132] - endometrial cancer Immunocytochemistry/Immunofluorescence: NIR2 Antibody [NBP2-34132] - Staining of human cell line A549 shows positivity in cytoplasm. Antibody staining is shown in green. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: NIR2 Antibody - Staining of human cell line HaCaT shows localization to cytosol. Immunocytochemistry/Immunofluorescence: NIR2 Antibody - Staining of human cell line HaCaT shows localization to cytosol & microtubule organizing center. 100 μL Log in to see 10 to 13 Days
$494.38
Details
Cow Goat Un-conjugated ELISA, WB   100 μg Log in to see 11 to 14 Days
$610.50
Details
Mouse Goat Un-conjugated ELISA   0.1 mg Log in to see 7 to 9 Days
$488.73
Details

Top referenced anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Antibodies

  1. Human Polyclonal PITPNM1 Primary Antibody for WB - ABIN4892952 : Aryal, Rao: Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitochondrial Damage in Human B-Lymphocytes. in PLoS ONE 2016 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Polyclonal PITPNM1 Primary Antibody for ELISA - ABIN250210 : Lev, Hernandez, Martinez, Chen, Plowman, Schlessinger: Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. in Molecular and cellular biology 1999 (PubMed)

More Antibodies against Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Interaction Partners

Mouse (Murine) Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) interaction partners

  1. Pitpnm1 null mice showed no hearing defects.

  2. results suggest that Nir2 not only enhances EMT in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

  3. RdgB homologs play a preemptive role in excluding endogenous and exogenous modified purine deoxyribonucleoside triphosphates (dTNPs) from incorporation into DNA.

Human Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) interaction partners

  1. results suggest that Nir2 not only enhances EMT in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

  2. Phosphatidic acid production triggers Phosphatidylinositol 4,5-Bisphosphate replenishment mediated by Nir2 and Nir3 at endoplasmic reticulum-plasma membrane junctions.

  3. Nir2 translocates from the Golgi complex to the plasma membrane in response to GF stimulation.

  4. Results suggest a feedback mechanism that replenishes PM PIP2 during receptor-induced Ca(2+) signaling via the Ca(2+) effector E-Syt1 and the PITP Nir2 at ER-PM junctions.

  5. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis.

  6. A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking & distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.

  7. Phosphorylation of Nir2 by Cdk1 facilitates its dissociation from the Golgi apparatus, and phospho-Nir2 is localized in the cleavage furrow and midbody during cytokinesis.

  8. Nir2 is involved in maintaining a critical DAG pool in the Golgi apparatus by regulating its consumption via the CDP-choline pathway

  9. RdgB homologs play a preemptive role in excluding endogenous and exogenous modified purine deoxyribonucleoside triphosphates (dTNPs) from incorporation into DNA.

Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Antigen Profile

Protein Summary

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005

Gene names and symbols associated with PITPNM1

  • phosphatidylinositol transfer protein membrane associated 1 (PITPNM1) antibody
  • phosphatidylinositol transfer protein, membrane-associated 1 (Pitpnm1) antibody
  • DRES9 antibody
  • Mpt-1 antibody
  • Nir-2 antibody
  • NIR2 antibody
  • PITPNM antibody
  • PITPnm 1 antibody
  • R75447 antibody
  • Rd9 antibody
  • RDGB antibody
  • RDGB1 antibody
  • RDGBA antibody
  • RDGBA1 antibody

Protein level used designations for PITPNM1

phosphatidylinositol transfer protein, membrane-associated 1 , phosphatidylinositol transfer protein, membrane-associated 1-like , membrane-associated phosphatidylinositol transfer protein 1-like , drosophila retinal degeneration B homolog 1 , membrane-associated phosphatidylinositol transfer protein 1 , pyk2 N-terminal domain-interacting receptor 2 , retinal degeneration 9 , NIR-2 , PITPnm 1 , PYK2 N-terminal domain-interacting receptor 2 , drosophila retinal degeneration B homolog , retinal degeneration B alpha 1 , phosphatidylinositol membrane-associated

GENE ID SPECIES
533859 Bos taurus
610462 Canis lupus familiaris
721716 Macaca mulatta
769912 Gallus gallus
100408084 Callithrix jacchus
100465754 Ailuropoda melanoleuca
100547262 Meleagris gallopavo
100586982 Nomascus leucogenys
100607998 Pan troglodytes
18739 Mus musculus
9600 Homo sapiens
361694 Rattus norvegicus
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