Phosphogluconate Dehydrogenase Proteins (PGD)

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Additionally we are shipping PGD Antibodies (91) and PGD Kits (8) and many more products for this protein.

Gene Name	GeneID	UniProt
PGD	5226	P52209
PGD	110208	Q9DCD0
PGD	100360180	P85968;

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Top PGD Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No.	Origin	Source	Conjugate	Quantity	Supplier	Delivery	Price	Details
ABIN3088314	Insect Cells	Human	His tag	1 mg	Log in to see	60 Days	$9,797.11	Details
ABIN3129646	Insect Cells	Mouse	His tag	1 mg	Log in to see	60 Days	$9,797.11	Details
ABIN1607963	Escherichia coli (E. coli)	Human	GST tag	1 mg	Log in to see	60 to 71 Days	$1,842.50	Details
ABIN2002762	Escherichia coli (E. coli)	Human	His tag	100 μg	Log in to see	20 to 21 Days	$327.80	Details
ABIN5777321	Escherichia coli (E. coli)	Human	His tag	0.5 mg	Log in to see	13 to 16 Days	$492.31	Details
ABIN1314798	Wheat germ	Human	GST tag	10 μg	Log in to see	11 to 12 Days	$414.29	Details
ABIN1472371	Yeast	Wild boar	His tag	1 mg	Log in to see	60 to 71 Days	$2,641.83	Details
ABIN1663100	Yeast	Fruit Fly	His tag	1 mg	Log in to see	60 to 71 Days	$3,358.67	Details
ABIN1473658	Yeast	Rat	His tag	1 mg	Log in to see	60 to 71 Days	$3,362.33	Details
ABIN1476801	Yeast	Sheep	His tag	1 mg	Log in to see	60 to 71 Days	$3,362.33	Details

PGD Proteins by Origin and Source

Origin	Expressed in	Conjugate
Human	, , , ,	,
Mouse (Murine)
Rat (Rattus)

More product categories related to PGD Protein

More Proteins for Phosphogluconate Dehydrogenase (PGD) Interaction Partners

Human Phosphogluconate Dehydrogenase (PGD) interaction partners

identified that 6-phosphogluconate dehydrogenase (6PGD) is critically involved in the development of anaplastic thyroid cancer (ATC (show SRPK1 Proteins)) resistance to doxorubicin. 6PGD inhibition disrupts metabolic reprogramming in doxorubicin-resistant ATC (show SRPK1 Proteins) cells.
Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1 (show STK11 Proteins)-AMPK (show PRKAA1 Proteins) signalling.
copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues
Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells.
Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation.
Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence
Data suggest that the affinity of Nox2 (show CYBB Proteins) for NADPH (show NQO1 Proteins) is increased in the presence of 6PGDH on cell stimulation.
Hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Mouse (Murine) Phosphogluconate Dehydrogenase (PGD) interaction partners

Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence
Taken together, these data suggest that ADD1/SREBP1c (show SREBF1 Proteins) is a key transcription factor for 6PGDH gene expression and would coordinate glucose metabolism and lipogenesis for energy homeostasis.

PGD Protein Profile

Protein Summary

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.

Gene names and symbols associated with PGD

phosphogluconate dehydrogenase (PGD)
Phosphogluconate dehydrogenase (Pgd)
phosphogluconate dehydrogenase (Pgd)
phosphogluconate dehydrogenase L homeolog (pgd.L)
phosphogluconate dehydrogenase (pgd)
6-phosphogluconate dehydrogenase, decarboxylating (GND1a|GND1b)
6-phosphogluconate dehydrogenase, decarboxylating (Thal_1580)
6-phosphogluconate dehydrogenase, decarboxylating (GY4MC1_3101)
6-phosphogluconate dehydrogenase, decarboxylating (Odosp_2189)
6-phosphogluconate dehydrogenase, decarboxylating (Marky_1024)
6-phosphogluconate dehydrogenase, decarboxylating (gnd)
6-phosphogluconate dehydrogenase, decarboxylating-like (LOC101451876)

6-pgd protein
6-PGDH protein
6Pgd protein
6pgdh protein
0610042A05Rik protein
A7 protein
AU019875 protein
C78335 protein
Cc2-27 protein
CG3724 protein
Dmel\\CG3724 protein
EG:87B1.4 protein
fi03d03 protein
GND1b protein
l(1)2Dc protein
l(1)2De protein
l(1)A7 protein
l(1)G0385 protein
l(1)N1 protein
l(1)N3[90] protein
l(1)Pgd protein
l(1)Pgd-A protein
l35 protein
N1 protein
Pdg protein
Pgd protein
wu:fi03d03 protein
zgc:55585 protein
zgc:111848 protein

Protein level used designations for PGD

6-phosphogluconate dehydrogenase, decarboxylating , 6-phosphogluconate , 6-phosphogluconate dehydrogenase , CG3724-PA , CG3724-PB , NADP-6 phosphogluconate dehydrogenase , Pgd-PA , Pgd-PB , dehydrogenase , phosphogluconate dehydrogenase , 6-phosphogluconate dehydrogenase (decarboxylating) , 6-phosphogluconate dehydrogenase, decarboxylating-like

GENE ID	SPECIES
5226	Homo sapiens
31185	Drosophila melanogaster
110208	Mus musculus
398848	Xenopus laevis
406762	Danio rerio
419450	Gallus gallus
443541	Ovis aries
514939	Bos taurus
5722476	Chlamydomonas reinhardtii
8815110	Thermocrinis albus DSM 14484
9929981	Geobacillus sp. Y4.1MC1
10253936	Odoribacter splanchnicus DSM 220712
10433922	Marinithermus hydrothermalis DSM 14884
10448388	Chlamydophila pecorum E58
100534626	Taeniopygia guttata
100598383	Nomascus leucogenys
397546	Sus scrofa
101451876	Ceratitis capitata
100360180	Rattus norvegicus
101788565	Cavia porcellus
101866917	Macaca fascicularis

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