PGD Protein (His tag)

Catalog No. ABIN7319375

Recombinant PGD protein expressed in HEK-293 Cells.

Quick Overview for PGD Protein (His tag) (ABIN7319375)

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This PGD protein is labelled with His tag.

Purpose: Recombinant Human PGD Protein (Human Cells, His Tag)

Sequence: Met 1-Ala483

Characteristics: Recombinant Human 6-phosphogluconate dehydrogenase is produced by our Mammalian expression system and the target gene encoding Met1-Ala483 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: PGD

Background: 6-phosphogluconate dehydrogenase,6PGD,Decarboxylating,PGD,PGDH,6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.

Molecular Weight:

Calculated MW: 54.2 kDa

Observed MW: 58 kDa

Gene ID: 5226

UniProt: P52209