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Pigeon Homolog (Drosophila) Proteins

Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300).

7 results:

Pigeon Homolog (Drosophila) (PION) (AA 734-854) protein (His tag) Protein

PION Origin: Human Source: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3081066
$5,702.88
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 30 to 35 Business Days

Pigeon Homolog (Drosophila) (PION) (AA 738-858) protein (His tag) Protein

PION Origin: Mouse Source: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3121788
$5,702.88
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 30 to 35 Business Days

Pigeon Homolog (Drosophila) (PION) (AA 1-854) protein (His tag) Protein

PION Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3092843
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

Pigeon Homolog (Drosophila) (PION) (AA 1-858) protein (His tag) Protein

PION Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3134967
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

Pigeon Homolog (Drosophila) (PION) (AA 616-854) protein (His tag,T7 tag) Protein

PION Origin: Human Source: Escherichia coli (E. coli) Recombinant > 95 % IP, SDS, ELISA, WB
Catalog No. ABIN1877517
$428.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 13 to 16 Business Days

Pigeon Homolog (Drosophila) (PION) Protein Protein

PION Origin: Human Source: Escherichia coli (E. coli) Recombinant > 95 % ELISA, IP, SDS, WB
Catalog No. ABIN3009545
$710.77
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 18 Business Days

Pigeon Homolog (Drosophila) (PION) Protein Protein

PION Origin: Rat Source: Escherichia coli (E. coli) Recombinant SDS, WB
Catalog No. ABIN6123031
$609.23
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 18 Business Days
  • Type Protein
    • Protein
  • Target Pigeon Homolog (Drosophila) (PION)
    • Pigeon Homolog (Drosophila) (PION)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Crystallization (Crys)
    • Immunoprecipitation (IP)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • Insect Cells
  • Binding Specificity
    • AA 1-854
    • AA 1-858
    • AA 616-854
    • AA 734-854
    • AA 738-858
  • Conjugate
    • Un-conjugated
    • His tag
    • His tag,T7 tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized

Pigeon Homolog (Drosophila) (PION) Protein Profile

Protein Summary

Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1\; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP\; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010

Gene names and symbols associated with PION

  • gamma-secretase activating protein (GSAP) antibody
  • gamma-secretase activating protein (Gsap) antibody
  • A530088I07Rik antibody
  • Pion antibody

Protein level used designations for PION

gamma-secretase-activating protein , pigeon homolog , protein pigeon homolog

GENE ID SPECIES
54103 Homo sapiens
212167 Mus musculus
311984 Rattus norvegicus

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