Pigeon Homolog (Drosophila) Proteins

Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300).

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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  • 1
Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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7 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3081066
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3121788
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3134967
$13,376.85
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 70 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3092843
$13,376.85
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 70 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2124921
$684.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3009545
$689.42
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityRat (Rattus)
Application SDS, WB
Order details Cat. No. ABIN6123031
$590.93
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
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Pigeon Homolog (Drosophila) (PION) Protein Profile

Protein Summary

Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1\; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP\; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010

Gene names and symbols associated with PION

  • gamma-secretase activating protein (GSAP) antibody
  • gamma-secretase activating protein (Gsap) antibody
  • A530088I07Rik antibody
  • Pion antibody

Protein level used designations for PION

gamma-secretase-activating protein , pigeon homolog , protein pigeon homolog

GENE ID SPECIES
54103 Homo sapiens
212167 Mus musculus
311984 Rattus norvegicus