GSAP Products
(Pigeon Homolog (PION))
Categories
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1\; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP\; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010].
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Featured GSAP Categories
GSAP Antibodies
High quality antibodies with extensive validation data.
GSAP ELISA Kits
Reliable ELISA kits for a wide range of species.
GSAP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GSAP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7439789
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN954149
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
Cat. No.
ABIN7441736
Quantity
100 μL
Datasheet
Datasheet
Recommended GSAP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969324
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958587
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1134367
Quantity
96 tests
Datasheet
Datasheet
Recommended GSAP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3081066
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3121788
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3092843
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to GSAP
gamma-secretase activating protein (GSAP), gamma-secretase activating protein (Gsap), A530088I07Rik, PION, PionProtein level used designations for GSAP
- gamma-secretase-activating protein
- pigeon homolog
- protein pigeon homolog
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