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p53/TP53-regulated repressor of Akt/AKT1 signaling. Additionally we are shipping PHLDA3 Antibodies (32) and PHLDA3 Kits (1) and many more products for this protein.
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p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor (By similarity).
pleckstrin homology-like domain, family A, member 3
, TDAG51/Ipl homolog 1
, pleckstrin homology-like domain family A member 3
, pleckstrin homology-like domain, family A, member 2
, TDAG/lpl homolog 1