anti-Pleckstrin and Sec7 Domain Protein (PSD) Antibodies

PSD encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. Additionally we are shipping PSD Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PSD 5662 A5PKW4
PSD 171381  
PSD 73728 Q5DTT2
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Top anti-PSD Antibodies at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: PSD Antibody [NBP2-15083] - Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE, antibody diluted at 1:500. Immunohistochemistry-Paraffin: PSD Antibody [NBP2-15083] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of PSD using anti-PSD antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat brain tissue lysates, Lane 2: mouse brain tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-PSD antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for PSD at approximately 130KD. The expected band size for PSD is at 109KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Rat Mouse Un-conjugated ICC, IEM, IF, WB Immunofluorescence staining in HaCaT cells with Psd monoclonal antibody, clone 6G6 . Immunoelectron microscopy from rat hippocampus. Using Psd monoclonal antibody, clone 6G6 . 100 μg Log in to see 11 to 12 Days
$460.00
Details
Rat Mouse Un-conjugated IF, IHC, WB Immunohistochemical localization of Psd in rat neocortex with Psd monoclonal antibody, clone 7E3 . Immunofluorescence staining from mouse backskin- basal, hair follicle and dermal with Psd monoclonal antibody, clone 7E3 . 100 μg Log in to see 11 to 12 Days
$460.00
Details
Human Mouse Un-conjugated IF, WB PSD MaxPab polyclonal antibody. Western Blot analysis of PSD expression in rat brain. Western Blot analysis of PSD expression in transfected 293T cell line by PSD MaxPab polyclonal antibody.<br><br>Lane1:PSD transfected lysate(112.64 KDa).<br>Lane2:Non-transfected lysate.<br> 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit HRP ELISA   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit FITC ELISA   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μg Log in to see 11 to 18 Days
$412.19
Details
Human Mouse Un-conjugated IF, WB   50 μg Log in to see 11 to 16 Days
$625.43
Details

PSD Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,

, ,
Rat (Rattus)
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,
Mouse (Murine)


More Antibodies against PSD Interaction Partners

Human Pleckstrin and Sec7 Domain Protein (PSD) interaction partners

  1. Arf GTPases are likely to be locally activated by EFA6 and in turn targeted to the Flemming body to complete cytokinesis.

  2. PSD expression might be a useful biomarker for epigenetic-based gastric cancer early diagnosis and may lead to the identification of new targets for pharmacological intervention.

  3. EFA6 is regulated by a negative feedback loop, which is mediated by an allosteric interaction of Arf6 (show ARF6 Antibodies)-GTP (show AK3 Antibodies) with a domain of EFA6 and monitors the activation of Arf1 (show ARF1 Antibodies) and Arf6 (show ARF6 Antibodies) differentially

  4. EFA6 participates in activation of Arf6 (show ARF6 Antibodies) around the cleavage furrow during cytokinesis.

  5. Aberrant methylation of PSD occurs in UC-associated colorectal mucosa, enabling circumvention of Rac1 immune responses governing neutrophil chemotaxis and apoptosis, and plays a pivotal role in the mechanisms underlying UC-associated carcinogenesis.

  6. Both levels of accumulation of F-actin and apoptosis were significantly decreased in specimens from UC patients with PSD methylation compared to those without PSD methylation.

  7. Pleckstrin (show PLEK Antibodies) is a critical molecule for proinflammatory cytokine secretion in response to elevated advanced glycation end products (AGE) in diabetes.

Mouse (Murine) Pleckstrin and Sec7 Domain Protein (PSD) interaction partners

  1. Arf6 exchange factor EFA6 and endophilin directly interact at the plasma membrane to control clathrin-mediated endocytosis.

  2. EFA6A regulates Arf6 (show ARF6 Antibodies)-mediated neurite formation through interaction with SNX1 (show SNX1 Antibodies).

  3. determined the complete primary sequence of mouse EFA6D (show PSD3 Antibodies) encoding a protein of 1004 amino acids with a calculated molecular weight of 111,207 Da.

  4. EFA6A may form a protein complex with alpha-actinin and activate ARF6 in close proximity of the actin cytoskeleton and membrane proteins in the dendritic spines

  5. EFA6A-ARF6 (show ARF6 Antibodies) pathway may play a specific role at a subcompartment of perisynaptic photoreceptor processes

  6. Results showed that EFA6A was first shown localized intensely in nuclei of spermatocytes of adult testes and suggested a possible involvement of EFA6A-ARF6 (show ARF6 Antibodies) signaling in the karyokinesis and cytokinesis.

PSD Antigen Profile

Protein Summary

This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PSD

  • pleckstrin and Sec7 domain containing (PSD) antibody
  • pleckstrin and Sec7 domain containing (Psd) antibody
  • 1110007H17Rik antibody
  • A930015K15 antibody
  • Efa6 antibody
  • Efa6a antibody
  • mKIAA2011 antibody
  • PSD1 antibody
  • Psdl antibody
  • TYL antibody

Protein level used designations for PSD

PH and SEC7 domain-containing protein 1 , exchange factor for ARF6 , pleckstrin homology and SEC7 domain-containing protein 1 , pleckstrin-Sec7 domains-containing , pleckstrin and Sec7 domain containing homolog

GENE ID SPECIES
486859 Canis lupus familiaris
5662 Homo sapiens
171381 Rattus norvegicus
73728 Mus musculus
523124 Bos taurus
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