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Receptor for SEMA4D. Additionally we are shipping Plexin B1 Antibodies (73) and Plexin B1 Kits (6) and many more products for this protein.
Showing 5 out of 11 products:
Plexin-B1 and -B2 play redundant or compensatory roles during forebrain development to ensure proper neuronal production and neocortical expansion.
Deletion of plexin-B1, the high affinity receptor for semaphorin 4D (show SEMA4D Proteins), significantly (one-way ANOVA; p < 0.001) reduced thrombus weight (- 40%) in oxidative venous thrombosis.
Sema (show SEMA3B Proteins) 4D/CD100 (show SEMA4D Proteins) is not only a ligand for plexin B1 but also a direct signaling receptor in mediating Sema (show SEMA3B Proteins) 4D/CD100 (show SEMA4D Proteins)-plexin B's biological functions.
In Erb (show ERBB2 Proteins)B-2-overexpressing murine breast cancer, ablation of Plexin-B1 genes strongly reduced metastases. Plexin-B1 has no effect on tumorigenesis o (show ERBB2 Proteins)r tumor growth but is require (show RHOA Proteins)d for m (show RHOC Proteins)etastasis of ErbB-2-dependent breast cancers in vivo.
Semaphorin 4D (show SEMA4D Proteins)-induced nitric oxide synthase (iNOS (show NOS2 Proteins)) and nitric oxide (NO) production are mediated through plexin-B1.
a lack of plexin-B1 did not impact on cortical development in vivo
LARG (show ARHGEF12 Proteins) plays a critical role in plexin-B1 signaling to stimulate Rho activation and cytoskeletal reorganization.
binding of Sema (show SEMA3B Proteins) 4D to Plexin B1 stimulates the tyrosine kinase (show TYRO3 Proteins) activity of Met
Results suggest that plexin-A1 (show PLXNA1 Proteins) and B1 interact in the adult brain and transduce semaphorin 3A (show SEMA3A Proteins) signaling in cooperation.
The mechanism of semaphorin D (show SEMA3A Proteins) in the activation of the MAPK (show MAPK1 Proteins) pathway via plexin-B1 is reported.
Analysis of the interaction of Plexin-B1 and Plexin-B2 (show PLXNB2 Proteins) with Rnd family proteins shows lack of binding specificity.
The positive expression of both Sema4D (show SEMA4D Proteins) and PlexinB1 was found to be an independent risk factor for a worse survival in colorectal cancer.
Loss of plexin B1 expression might play a pivotal role in enhancing the metastatic potential of breast cancer cells.
Plexin B1 expression was regulated by TMPRSS2-ERG fusion gene in prostate cancer.
Plexin-B1 mediates RhoA (show RHOA Proteins)/integrin alphavbeta3 (show ITGAV Proteins) involved in the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) pathway and SRPK1 (show SRPK1 Proteins) to influence the growth of glioma cell, angiogenesis, and motility in vitro and in vivo.
results show that Sema4D (show SEMA4D Proteins)/plexin-B1 signaling promotes the translocation of androgen receptor (show AR Proteins) to the nucleus and thereby enhances AR transcriptional activity
Plexin-B1 induces cutaneous squamous cell carcinoma cell proliferation, migration, and invasion by interacting with Sema4D (show SEMA4D Proteins). Plexin-B1 might serve as a useful biomarker and/or as a novel therapeutic target for cSCC (show CYP11A1 Proteins).
Results show that decreased expression of Sema4D (show SEMA4D Proteins), plexin-B1 and -B2 was associated with local recurrence and poor prognosis of breast neoplasm.
Dysregulation of the vascular endothelial growth factor and semaphorin ligand-receptor families in prostate cancer metastasis
Blocking of CD100 (show SEMA4D Proteins), plexin B1 and/or B2 in adhesion experiments have shown that both CD100 (show SEMA4D Proteins) and plexins act as adhesion molecules involved in monocyte-endothelial cell binding.
Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
, plexin b1
, plexin 5
, semaphorin receptor SEP