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PCBP2 Proteins

(Poly(rC) Binding Protein 2 (PCBP2))

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

recommended

PCBP2 Protein (AA 1-362) (GST tag) (ABIN1314129)

PCBP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

PCBP2 Protein (AA 174-283) (GST tag) (ABIN1314131)

PCBP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

PCBP2 Protein (AA 1-365) (Strep Tag) (ABIN3085703)

Crystallography grade PCBP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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PCBP2 Proteins by Grade

Find PCBP2 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PCBP2 Proteins by Origin

Find PCBP2 Proteins for a variety of species such as anti-Human PCBP2, anti-Mouse PCBP2. The species listed below are among those available. Click on a link to go to the corresponding products.

PCBP2 Proteins by Source

Here you will find PCBP2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PCBP2 Proteins by Protein Type

Here you can find PCBP2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

PCBP2 Proteins by Application

Find PCBP2 Proteins validated for a specific application such as AbP, STD, ELISA, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PCBP2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

PCBP2 Protein (AA 1-362) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1314129

Quantity 10 μg

Datasheet Datasheet

PCBP2 Protein (AA 174-283) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1314131

Quantity 10 μg

Datasheet Datasheet

PCBP2 Protein (AA 1-365) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3085703

Quantity 1 mg

Datasheet Datasheet

PCBP2 Protein (AA 1-362) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3123103

Quantity 1 mg

Datasheet Datasheet

PCBP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2728353

Quantity 20 μg

Datasheet Datasheet

PCBP2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2728352

Quantity 20 μg

Datasheet Datasheet

PCBP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2728354

Quantity 20 μg

Datasheet Datasheet

PCBP2 Protein (Transcript Variant 7) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2728355

Quantity 20 μg

Datasheet Datasheet

PCBP2 Protein (Transcript Variant 6) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2728356

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our PCBP2 Proteins

Školáková, Foldynová-Trantírková, Bednářová, Fiala, Vorlíčková, Trantírek: "Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA." in: Nucleic acids research, Vol. 43, Issue 9, pp. 4733-45, (2015) (PubMed).

Wang, Jeng, Lai et al.: "Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral ..." in: Journal of virology, Vol. 85, Issue 16, pp. 7954-64, (2011) (PubMed).

Aliases for PCBP2 Proteins

poly(rC) binding protein 2 (PCBP2) Proteins
poly(rC) binding protein 2 (Pcbp2) Proteins
poly(rC) binding protein 2 (pcbp2) Proteins
poly(rC) binding protein 2 L homeolog (pcbp2.L) Proteins
alphaCP-2 Proteins
AW412548 Proteins
fb36h02 Proteins
hnRNP-E2 Proteins
HNRNPE2 Proteins
HNRPE2 Proteins
Hnrpx Proteins
PCBP2 Proteins
PCBP3 Proteins
wu:fb36h02 Proteins
zgc:55964 Proteins

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Popular PCBP2 Proteins

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Aliases for PCBP2 Proteins

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