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The protein encoded by PARP3 belongs to the PARP family. Additionally we are shipping PARP3 Antibodies (92) and many more products for this protein.
Showing 6 out of 6 products:
Parp3 is crucial in the early stages of zebrafi (show ARHGEF16 Proteins)sh development, possibly by exerting its transcriptional regulatory functions as early as during the specification of the neural plate border
PARP3 controls of TGFbeta (show TGFB1 Proteins)-induced epithelial mesenchymal transformation and acquisition of stem-like cell features by stimulation transglutaminase 2 (show TGM2 Proteins)/SNAI1 (show SNAI1 Proteins) signaling.
Data indicate that PARP3, a DNA damage-activated ADP-ribosyltransferase, can mono-ADP-ribosylate double-stranded DNA ends.
In a process of single-strand DNA repair, PARP3 mono-ADP-ribosylates nucleosomal histone H2B.
we found that PARP3 interacted with FoxM1 (show FOXM1 Proteins) to enhance its transcriptional activity and conferred glioblastoma cell radioresistance. Thus, our data suggest that PARP3 could be a therapeutic target to overcome radioresistance in glioblastoma
Identification of ADP-ribosylation sites in PARP3 and the determination of the extent ofpoly(ADP-ribosyl)ated residues in this protein was performed.
MiR (show MLXIP Proteins)-630 reduced apoptosis by downregulating several apoptotic modulators, PARP3, DDIT4 (show DDIT4 Proteins), and EP300 (show EP300 Proteins).
In some cancer cells, repression of PARP3 could be responsible for an increased telomerase activity.
PARP3 likely facilitates the recruitment of Ku80 (show XRCC5 Proteins) to double strand breaks to antagonize DNA end resection but facilitate Ku-mediated accurate classical non-homologous end-joining.
PARP3 gene occupancy in the human neuroblastoma (show ARHGEF16 Proteins) cell line SK-N-SH occurs preferentially with developmental genes regulating cell fate specification, tissue patterning, craniofacial development and neurogenesis.
PARP3 is a critical player in the stabilization of the mitotic spindle and in telomere integrity by associating and regulating the mitotic components NuMA and tankyrase 1 (show TNKS Proteins).
We show that Poly(ADP)ribose polymerase 3 (Parp3), an enzyme recently implicated in DNA repair, contributes to antibody diversification by negatively regulating class switch recombination without affecting somatic hypermutation.
PARP-3 has a role in chromosomal DNA double-strand break repair.
We cloned and sequenced the cDNAs of the mouse PARP-3 (Adprt3) gene encoding poly(ADP-ribose) polymerase 3 and of the closely linked U3-55k (show RRP9 Proteins) gene coding for the U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein.
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
NAD(+) ADP-ribosyltransferase 3
, poly [ADP-ribose] polymerase 3
, poly[ADP-ribose] synthase 3
, ADP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3
, poly (ADP-ribose) polymerase family, member 3
, Poly synthetase 3
, poly [ADP-ribose] polymerase 3-like
, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2
, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3
, ADP-ribosyltransferase diphtheria toxin-like 3
, NAD+ ADP-ribosyltransferase 3
, poly(ADP-ribose) synthetase-3
, poly[ADP-ribose] synthetase 3
, A DP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3
, ADP-ribosyltransferase (NAD+, poly (ADP-ribose polymerase)-like 3
, Poly[ADP-ribose] synthetase-3
, poly (ADP-ribosyl) transferase-like 3