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PARP3 Protein (GST tag,His tag)

PARP3 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317627
  • Target See all PARP3 Proteins
    PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This PARP3 protein is labelled with GST tag,His tag.
    Purpose
    Recombinant Human PARP-3/PARP3 Protein (His & GST Tag)
    Sequence
    Met 1-Leu 533
    Characteristics
    A DNA sequence encoding the C-terminal segment of human PARP3 isoform 1 (Q9Y6F1-1) (Met 1-Leu 533) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
    Purity
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product PARP3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
    Alternative Name
    PARP-3/PARP3 (PARP3 Products)
    Synonyms
    ADPRT-3 Protein, PARP-3 Protein, PM38 Protein, Adprtl3 Protein, fj17c06 Protein, wu:fj17c06 Protein, zgc:66157 Protein, PARP3 Protein, parp3 Protein, ADPRT3 Protein, ADPRTL2 Protein, ADPRTL3 Protein, ARTD3 Protein, IRT1 Protein, PADPRT-3 Protein, A930002C11Rik Protein, AW990611 Protein, Adprt3 Protein, pADPRT-3 Protein, seed maturation protein PM38 Protein, poly (ADP-ribose) polymerase family, member 3 Protein, poly(ADP-ribose) polymerase family member 3 Protein, poly(ADP-ribose) polymerase family member 3 L homeolog Protein, PARP3 Protein, parp3 Protein, parp3.L Protein, Parp3 Protein
    Background

    Background: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.

    Synonym: ADPRT3,ADPRTL2,ADPRTL3,ARTD3,IRT1,PADPRT-3

    Molecular Weight
    87.8 kDa
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