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Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Additionally we are shipping PAIP2 Antibodies (64) and and many more products for this protein.
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Paip2 is a host antiviral restriction factor antagonized by PABP accumulation in HCMV-infected cells
Role of PAIP2 in modulation of GLUT5 mRNA stability.
PAIP2 is a crucial regulator of VEGF (show VEGFA Proteins) mRNA and has a role in regulating angiogenesis
The turnover of Paip2 in the cell is mediated by EDD and is regulated by PABP.
this study demonstrated that activity-dependent degradation of PAIP2A relieves translational inhibition of memory-related genes through PABP (show EBP Proteins) reactivation and conclude that PAIP2A is a pivotal translational regulator of synaptic plasticity and memory.
PABP (show EBP Proteins) interacting protein 2A (PAIP2A) regulates specific key proteins during spermiogenesis in the mouse.
Paip2 is able to function as a tumor suppressor
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
PABC1-interacting protein 2
, PABP-interacting protein 2
, poly(A)-binding protein-interacting protein 2
, polyA-binding protein-interacting protein 2
, polyadenylate-binding protein-interacting protein 2
, polyadenylate-binding protein interacting protein 2
, poly(A) binding protein interacting protein 2
, spoly(A) binding protein interacting protein 2
, Pabp-interacting protein 2
, poly(A) binding protein interacting protein 2B L homeolog