PAIP2 Protein (AA 1-127) (His tag)

Catalog No. ABIN666906

Product Details

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Protein Type: Recombinant

Protein Characteristics: AA 1-127

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PAIP2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: PAIP2, 1-127 aa, Human, His-tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Alternative Name: PAIP2 (PAIP2 Products)

Synonyms: PAIP2A Protein, DKFZp469O1314 Protein, 2310050K10Rik Protein, AU045972 Protein, paip2 Protein, poly(A) binding protein interacting protein 2 Protein, polyadenylate-binding protein-interacting protein 2 Protein, poly(A) binding protein interacting protein 2B L homeolog Protein, PAIP2 Protein, Paip2 Protein, paip2b.L Protein

Background: PAIP2, also known as Poly(A)-binding protein-interacting protein 2, acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. Recombinant PAIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PAIP2A, PABP- interacting protein 2, HSPC218, Poly(A)-binding protein-interacting protein 2 poly(A) binding protein interacting protein 2. NCBI no.: NP_057564

Molecular Weight: 17.1 kDa (147aa), confirmed by MALDI-TOF.