POLG Proteins
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit.
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Polymerase (DNA Directed), gamma (POLG) (AA 1-1239) protein (His tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 1-1218) protein (His tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 1041-1239) protein (S tag,His tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 1130-1239) protein (GST tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 575-866) protein (His-SUMO Tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 575-866) protein (His tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 571-857) protein (His tag) Protein
Polymerase (DNA Directed), gamma (POLG) (AA 192-325), (partial) protein (His-SUMO Tag) Protein
POLG Protein Profile
Protein Summary
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Gene names and symbols associated with POLG
- polymerase (DNA) gamma, catalytic subunit L homeolog (polg.L) antibody
- DNA polymerase gamma, catalytic subunit (Polg) antibody
- DNA polymerase gamma, catalytic subunit (POLG) antibody
- polymerase (DNA directed), gamma (POLG) antibody
- polymerase (DNA directed), gamma (polg) antibody
- polymerase (DNA directed), gamma (Polg) antibody
- AA409516 antibody
- MDP1 antibody
- MIRAS antibody
- MTDPS4A antibody
- MTDPS4B antibody
- PEO antibody
- POLG antibody
- POLG1 antibody
- PolgA antibody
- SANDO antibody
- SCAE antibody
Protein level used designations for POLG
DNA polymerase gamma , DNA polymerase subunit gamma-1 , DNA-directed DNA polymerase gamma , mitochondrial DNA polymerase catalytic subunit , polG-alpha , polymerase (DNA directed), gamma , DNA polymerase subunit gamma-1-like , PolG-alpha , DNA polymerase gamma subunit 1 (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) , Pol gamma , mitochondrial DNA polymerase gamma , mitochondrial DNA polymerase-gamma , mitochondrial polymerase gamma , polymerase, gamma
GENE ID | SPECIES |
---|---|
397851 | Xenopus laevis |
85472 | Rattus norvegicus |
404292 | Gallus gallus |
467754 | Pan troglodytes |
488732 | Canis lupus familiaris |
699750 | Macaca mulatta |
100038061 | Xenopus (Silurana) tropicalis |
100053827 | Equus caballus |
100408039 | Callithrix jacchus |
5428 | Homo sapiens |
18975 | Mus musculus |
100150924 | Danio rerio |
100728907 | Cavia porcellus |
100157469 | Sus scrofa |
533090 | Bos taurus |
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