POLR3C Proteins
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
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Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) protein (His tag) Protein
Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-533) protein (His tag) Protein
Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) protein (GST tag) Protein
Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 1-534) protein (GST tag) Protein
Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) (AA 151-260) protein (GST tag) Protein
Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C) protein (Myc-DYKDDDDK Tag) Protein
POLR3C Protein Profile
Protein Summary
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB- DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene names and symbols associated with POLR3C
- polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog (polr3c.S) antibody
- RNA polymerase III subunit C (POLR3C) antibody
- polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C) antibody
- polymerase (RNA) III (DNA directed) polypeptide C (62kD) (polr3c) antibody
- polymerase (RNA) III (DNA directed) polypeptide C (Polr3c) antibody
- RNA polymerase III subunit C (Polr3c) antibody
- polymerase (RNA) III (DNA directed) polypeptide C (polr3c) antibody
- 4933407E01Rik antibody
- RPC3 antibody
- RPC62 antibody
- zgc:56348 antibody
Protein level used designations for POLR3C
polymerase (RNA) III (DNA directed) polypeptide C (62kD) , DNA-directed RNA polymerase III subunit RPC3-like , DNA-directed RNA polymerase III subunit C , DNA-directed RNA polymerase III subunit RPC3 , RNA polymerase III subunit C3 , DNA-directed III 62 kDa polypeptide , RNA polymerase III 62 kDa subunit
GENE ID | SPECIES |
---|---|
446308 | Xenopus laevis |
457224 | Pan troglodytes |
483159 | Canis lupus familiaris |
776505 | Gallus gallus |
100014746 | Monodelphis domestica |
100341275 | Oryctolagus cuniculus |
100380066 | Xenopus (Silurana) tropicalis |
100401836 | Callithrix jacchus |
100431311 | Pongo abelii |
100589512 | Nomascus leucogenys |
74414 | Mus musculus |
310685 | Rattus norvegicus |
393201 | Danio rerio |
10623 | Homo sapiens |
507314 | Bos taurus |