POLR3C Proteins

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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  • 1
Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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7 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3095111
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3137090
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315704
$338.33
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315705
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315707
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 %
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5711825
$456.50
Plus shipping costs $45.00
Will be delivered in 11 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729330
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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POLR3C Protein Profile

Protein Summary

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB- DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Gene names and symbols associated with POLR3C

  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog (polr3c.S) antibody
  • RNA polymerase III subunit C (POLR3C) antibody
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C) antibody
  • polymerase (RNA) III (DNA directed) polypeptide C (62kD) (polr3c) antibody
  • polymerase (RNA) III (DNA directed) polypeptide C (Polr3c) antibody
  • RNA polymerase III subunit C (Polr3c) antibody
  • polymerase (RNA) III (DNA directed) polypeptide C (polr3c) antibody
  • 4933407E01Rik antibody
  • RPC3 antibody
  • RPC62 antibody
  • zgc:56348 antibody

Protein level used designations for POLR3C

polymerase (RNA) III (DNA directed) polypeptide C (62kD) , DNA-directed RNA polymerase III subunit RPC3-like , DNA-directed RNA polymerase III subunit C , DNA-directed RNA polymerase III subunit RPC3 , RNA polymerase III subunit C3 , DNA-directed III 62 kDa polypeptide , RNA polymerase III 62 kDa subunit

GENE ID SPECIES
446308 Xenopus laevis
457224 Pan troglodytes
483159 Canis lupus familiaris
776505 Gallus gallus
100014746 Monodelphis domestica
100341275 Oryctolagus cuniculus
100380066 Xenopus (Silurana) tropicalis
100401836 Callithrix jacchus
100431311 Pongo abelii
100589512 Nomascus leucogenys
74414 Mus musculus
310685 Rattus norvegicus
393201 Danio rerio
10623 Homo sapiens
507314 Bos taurus
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