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POLR3C Products

(Polymerase (RNA) III (DNA Directed) Polypeptide C (62kD) (POLR3C))

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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB- DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

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Featured POLR3C Categories

POLR3C Antibodies

High quality antibodies with extensive validation data.

POLR3C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLR3C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), IHC
Validations
  • (11)
Cat. No. ABIN1500340
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN524053
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN524051
Quantity 50 μL
Datasheet Datasheet

Recommended POLR3C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315705
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315707
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095111
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to POLR3C

polymerase (RNA) III (DNA directed) polypeptide C (62kD) S homeolog (polr3c.S), RNA polymerase III subunit C (POLR3C), polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C), polymerase (RNA) III (DNA directed) polypeptide C (62kD) (polr3c), polymerase (RNA) III (DNA directed) polypeptide C (Polr3c), RNA polymerase III subunit C (Polr3c), polymerase (RNA) III (DNA directed) polypeptide C (polr3c), 4933407E01Rik, rpc3, RPC3, rpc62, RPC62, zgc:56348

Protein level used designations for POLR3C

  • polymerase (RNA) III (DNA directed) polypeptide C (62kD)
  • DNA-directed RNA polymerase III subunit RPC3-like
  • DNA-directed RNA polymerase III subunit C
  • DNA-directed RNA polymerase III subunit RPC3
  • RNA polymerase III subunit C3
  • DNA-directed III 62 kDa polypeptide
  • RNA polymerase III 62 kDa subunit
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