anti-Potassium Channel, Subfamily K, Member 16 (KCNK16) Antibodies

The protein encoded by KCNK16 belongs to the family of potassium channel proteins containing two pore-forming P domains. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat KCNK16 KCNK16 688996  
KCNK16 83795 Q96T55
Anti-Mouse KCNK16 KCNK16 74571  
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Top anti-KCNK16 Antibodies at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Biotin ELISA   100 μg 11 to 18 Days
$464.30
Details
Human Rabbit FITC ELISA   100 μg 11 to 18 Days
$464.30
Details
Human Rabbit HRP ELISA   100 μg 11 to 18 Days
$464.30
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μg 11 to 18 Days
$464.30
Details
Human Rabbit Un-conjugated IHC, WB   100 μL 7 to 8 Days
$454.67
Details

More Antibodies against KCNK16 Interaction Partners

Human Potassium Channel, Subfamily K, Member 16 (KCNK16) interaction partners

  1. data establish TALK-1 channels as key regulators of beta cell ER Ca(2+) and suggest that TALK-1 may be a therapeutic target to reduce ER Ca(2+) handling defects in beta cells during the pathogenesis of diabetes.

  2. The TALK-1/iOPN complex caused Vm hyperpolarization and reduced beta-cell glucose-stimulated Ca2+ influx, which is predicted to inhibit glucose stimulated insulin secretion.

  3. These findings reveal TALK-1 channels as important modulators of second-phase insulin secretion and suggest a clinically relevant mechanism for rs1535500, which may increase type 2 diabetes risk by limiting glucose-stimulated insulin secretion.

  4. at least two functional TALK-1 variants are present and may serve as background K+ currents in certain cells of the human pancreas.

Mouse (Murine) Potassium Channel, Subfamily K, Member 16 (KCNK16) interaction partners

  1. TALK-1 reduces delta-cell cytosolic Ca2+ elevations and somatostatin release by limiting delta-cell Ca2+-induced Ca2+ release.

  2. data establish TALK-1 channels as key regulators of beta cell ER Ca(2+) and suggest that TALK-1 may be a therapeutic target to reduce ER Ca(2+) handling defects in beta cells during the pathogenesis of diabetes.

KCNK16 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with KCNK16

  • potassium two pore domain channel subfamily K member 16 (KCNK16) antibody
  • potassium two pore domain channel subfamily K member 16 (Kcnk16) antibody
  • potassium channel, subfamily K, member 16 (Kcnk16) antibody
  • 4731413G05Rik antibody
  • K2p16.1 antibody
  • TALK-1 antibody
  • TALK1 antibody

Protein level used designations for KCNK16

potassium channel, subfamily K, member 16 , potassium channel subfamily K member 16 , 2P domain potassium channel Talk-1 , TWIK-related alkaline pH-activated K(+) channel 1 , pancreatic potassium channel Talk-1

GENE ID SPECIES
462667 Pan troglodytes
481781 Canis lupus familiaris
688996 Rattus norvegicus
772022 Gallus gallus
83795 Homo sapiens
74571 Mus musculus
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