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Several different potassium channels are known to be involved with electrical signaling in the nervous system. Additionally we are shipping KCNJ4 Proteins (5) and many more products for this protein.
Showing 10 out of 78 products:
Mammalian Monoclonal KCNJ4 Primary Antibody for ISt, IHC - ABIN1304739
Cazorla, Shegda, Ramesh, Harrison, Kellendonk: Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Show all 2 Pubmed References
Increased excitability and decreased dendritic arborization are associated with downregulation of inward rectifier potassium channels (Kir2.1 (show KCNJ2 Antibodies)/2.3).
Kir2.2 (show KCNJ12 Antibodies) and Kir2.1 (show KCNJ2 Antibodies) are primary determinants of endogenous K(+) conductance in HAECs under resting conditions and that Kir2.2 (show KCNJ12 Antibodies) provides the dominant conductance in these cells.
Results describe the regulation of inwardly rectifying potassium current and its main molecular correlates, Kir2.1 (show KCNJ2 Antibodies), Kir2.2 (show KCNJ12 Antibodies) and Kir2.3 channels, by endothelin-1 (show EDN1 Antibodies) in human atrial cardiomyocytes.
Kir2.3 is internalized by an AP-2 clathrin-dependent mechanism.
possibility of intramolecular interactions of the residue Kir2.3(H117) with conserved cysteines in close proximity to the selectivity filter
The data suggest that Kir2.3 plays a potentially important role in I(K1) currents in neonatal rat cardiomyocytes.
TIP-1 (show TAX1BP3 Antibodies) may act as an important regulator for the endocytic pathway of Kir2.3.
changes in these proteins and their modification may predispose striatal projection neurons to dysfunction and then degeneratation in Huntington disease (show HTT Antibodies)
K+ currents attributable to Kir2.2 (show KCNJ12 Antibodies)/2.3 and K+-selective leak (Kleak) channels are prominent in layer V-VI pyramidal neurons in slices of prelimbic and infralimbic cortex
Kir2.3 channels do not contribute to cardiac inward rectifier (show KCNJ5 Antibodies) potassium currents.
Enhanced interaction with PIP(2) is the molecular mechanism for Kir2.3 channel activation by arachidonic acid.
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
potassium inwardly-rectifying channel, subfamily J, member 4
, inward-rectifying potassium channel cKir2.3
, potassium inwardly-rectifying channel J4
, hippocampal inward rectifier potassium channel
, inward rectifier K(+) channel Kir2.3
, inward rectifier K+ channel Kir2.3
, inward rectifier potassium channel 4
, potassium channel, inwardly rectifying subfamily J member 4
, Kir 2.3
, brain inwardly rectifying K(+) channel 2