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KCNQ5 is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. Additionally we are shipping KCNQ5 Proteins (3) and many more products for this protein.
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Dog (Canine) Polyclonal KCNQ5 Primary Antibody for ELISA - ABIN451813
Schuetz, Kumar, Poronnik, Adams: Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. in American journal of physiology. Cell physiology 2008
Our data support the involvement of KCNQ5 gene polymorphisms in the genetic susceptibility to high myopia and further exploration of KCNQ5 as a risk factor for high myopia.
These findings provide the first evidence linking PKC (show PRRT2 Antibodies) activation to suppression of Kv7 currents, membrane depolarization, and Ca(2 (show CA2 Antibodies)+) influx via L (show COX6A1 Antibodies)-type voltage-sensitive Ca(2 (show CA2 Antibodies)+) channels as a mechanism for histamine-induced bronchoconstriction.
both loss-of-function and gain-of-function KCNQ5 mutations, associated with increased excitability and decreased repolarization reserve, lead to pathophysiology.
Tannic acid activates Kv7.4 (show KCNQ4 Antibodies) and Kv7.3 (show KCNQ3 Antibodies)/7.5 K(+) channels resulting in vasodilation.
rs9351963 in KCNQ5 is a possible predictive factor of incidence of diarrhea in cancer patients treated with irinotecan chemotherapy.
suggestive loci for periodontitis: KCNQ5 on chromosome 6q13 in a Japanese population. study should contribute to further understanding of genetic factors for enhanced susceptibility to periodontitis.
Kv7.1 (show KCNQ1 Antibodies)/Kv7.5 form heterotetrameric channels increasing the diversity of structures which fine-tune blood vessel reactivity. The lipid raft localization of Kv7.1 (show KCNQ1 Antibodies)/Kv7.5 heteromers provides efficient spatial and temporal regulation of smooth muscle function.
Differential protein kinase C (show PKC Antibodies)-dependent modulation of Kv7.4 (show KCNQ4 Antibodies) and Kv7.5 subunits of vascular Kv7 channels.
characterized the cell-type specific spatial organization of the kcnq5 gene locus mediated by CTCF (show CTCF Antibodies) in detail using chromosome conformation capture (3C) and 3C-derived techniques
The results of this study indicated that Kv7.5 contributes to the spatial regulation of KCNE3 (show Kcne3 Antibodies).
KCNQ5 controls excitability and function of hippocampal networks through modulation of synaptic inhibition.
analysis of the vestibular role of KCNQ4 (show KCNQ4 Antibodies) and KCNQ5 K+ channels revealed by mouse models
Data show that in early pregnant mouse myometrium, the relative abundance of mRNA expression was KCNQ3 (show KCNQ3 Antibodies) > KCNQ4 (show KCNQ4 Antibodies) > KCNQ5 > KCNQ1 (show KCNQ1 Antibodies) > KCNQ2 (show KCNQ2 Antibodies).
Kcnq5(dn/dn (show TMC1 Antibodies)) mice are viable and have normal brain morphology. However, in the CA3 (show CA3 Antibodies) area of hippocampus, a region that highly expresses KCNQ5 channels, the medium and slow afterhyperpolarization currents are significantly reduced.
Data show that murine KCNQ5 channels are tightly regulated by changes in extracellular Zn2+, pH, and tonicity, thus adding to the complex regulation of these channels.
Murine blood vessels exhibit a distinctive expression profile of KCNQ1 (show KCNQ1 Antibodies), KCNQ4 (show KCNQ4 Antibodies), and KCNQ5, with 'neuronal' KCNQ4 (show KCNQ4 Antibodies) dominating
These data represent an exhaustive characterisation of a truncated KCNQ5 splice variant that may contribute to the native XE991-sensitive channel in murine vasculature.
Results provide support for KCNQ4 (show KCNQ4 Antibodies)- or KCNQ5-encoded channels having an important functional impact in the vasculature.
K(v)7.4 (show KCNQ4 Antibodies) and K(v)7.5 are expressed in different regions of the murine gastrointestinal tract and blockers of K(v)7 channels augment inherent contractile activity.
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.
potassium voltage-gated channel, KQT-like subfamily, member 5
, potassium voltage-gated channel subfamily KQT member 5-like
, potassium voltage-gated channel subfamily KQT member 5
, potassium voltage-gated channel, subfamily Q, member 5
, KQT-like 5
, potassium channel protein
, potassium channel subunit alpha KvLQT5
, voltage-gated potassium channel subunit Kv7.5
, voltage-gated potassium channel type Kv7.5