anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5) Antibodies

KCNQ5 is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. Additionally we are shipping KCNQ5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNQ5 259273  
KCNQ5 56479 Q9NR82
KCNQ5 226922 Q9JK45
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Top anti-KCNQ5 Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-KCNQ5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . Dilution: 1:500~1000 Western Blot analysis of KCNQ5 expression in transfected 293T cell line by KCNQ5 monoclonal antibody (M01), clone 2E2.Lane 1: KCNQ5 transfected lysate (Predicted MW: 46.9 KDa).Lane 2: Non-transfected lysate. Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Rabbit Un-conjugated WB Observed bind size: 102KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 μg of whole cell lysate) A:293T 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KCNQ5 Antibody (C-term) in mouse heart tissue lysates (35ug/lane). This demonstrates the KCNQ5 antibody detected the KCNQ5 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6275387 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: Kv7.5 Antibody [NBP1-82861] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. Immunocytochemistry/Immunofluorescence: Kv7.5 Antibody  - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details

Top referenced anti-KCNQ5 Antibodies

  1. Dog (Canine) Polyclonal KCNQ5 Primary Antibody for ELISA - ABIN451813 : Schuetz, Kumar, Poronnik, Adams: Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. in American journal of physiology. Cell physiology 2008 (PubMed)

More Antibodies against KCNQ5 Interaction Partners

Human Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5) interaction partners

  1. Phylogenetic analysis, electrostatic potential mapping, in silico docking, electrophysiology, and radioligand binding assays reveal that the anticonvulsant binding pocket evolved to accommodate endogenous neurotransmitters including gamma-aminobutyric acid, which directly activates KCNQ5 and KCNQ3 via W265.

  2. Phosphorylation of S53 on the amino terminus of Kv7.5 is essential for protein kinase A-dependent enhancement of channel activity in response to beta adrenergic receptor activation in vascular and airway smooth muscle cells.

  3. identified P2RX2, KCNQ5, ERBB3 and SOCS3 to be associated with the progression of age-related hearing impairment

  4. Our data support the involvement of KCNQ5 gene polymorphisms in the genetic susceptibility to high myopia and further exploration of KCNQ5 as a risk factor for high myopia.

  5. These findings provide the first evidence linking PKC activation to suppression of Kv7 currents, membrane depolarization, and Ca(2+) influx via L-type voltage-sensitive Ca(2+) channels as a mechanism for histamine-induced bronchoconstriction.

  6. both loss-of-function and gain-of-function KCNQ5 mutations, associated with increased excitability and decreased repolarization reserve, lead to pathophysiology.

  7. Tannic acid activates Kv7.4 and Kv7.3/7.5 K(+) channels resulting in vasodilation.

  8. rs9351963 in KCNQ5 is a possible predictive factor of incidence of diarrhea in cancer patients treated with irinotecan chemotherapy.

  9. suggestive loci for periodontitis: KCNQ5 on chromosome 6q13 in a Japanese population. study should contribute to further understanding of genetic factors for enhanced susceptibility to periodontitis.

  10. Kv7.1/Kv7.5 form heterotetrameric channels increasing the diversity of structures which fine-tune blood vessel reactivity. The lipid raft localization of Kv7.1/Kv7.5 heteromers provides efficient spatial and temporal regulation of smooth muscle function.

  11. Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels.

  12. characterized the cell-type specific spatial organization of the kcnq5 gene locus mediated by CTCF in detail using chromosome conformation capture (3C) and 3C-derived techniques

  13. The results of this study indicated that Kv7.5 contributes to the spatial regulation of KCNE3.

  14. Data show that KCNQ1 mRNA expression was increased and KCNQ5 decreased in the preterm preeclamptic women.

  15. While KCNE1 slows activation and suppresses inward rectification, KCNE3 drastically inhibits KCNQ5 currents.

  16. Src associates with KCNQ2-5 subunits but phosphorylates only KCNQ3-5.

  17. In conclusion, this work demonstrates that inactivation is a key regulatory mechanism of Kv7.4 and Kv7.5 channels.

  18. among the allowed assembly conformations are KCNQ3/4 and KCNQ4/5 heteromers.

KCNQ5 Antigen Profile

Protein Summary

This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNQ5

  • potassium voltage-gated channel subfamily Q member 5 (KCNQ5) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 5a (kcnq5a) antibody
  • potassium voltage-gated channel subfamily Q member 5 (Kcnq5) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 5 (KCNQ5) antibody
  • potassium voltage-gated channel, subfamily Q, member 5 (Kcnq5) antibody
  • 7730402H11 antibody
  • 9230107O05Rik antibody
  • AA589396 antibody
  • D1Mgi1 antibody
  • KCNQ5 antibody
  • Kcnq5l antibody
  • Kv7.5 antibody
  • si:dkey-29l6.1 antibody

Protein level used designations for KCNQ5

potassium voltage-gated channel, KQT-like subfamily, member 5 , potassium voltage-gated channel subfamily KQT member 5-like , potassium voltage-gated channel subfamily KQT member 5 , potassium voltage-gated channel, subfamily Q, member 5 , KQT-like 5 , potassium channel protein , potassium channel subunit alpha KvLQT5 , voltage-gated potassium channel subunit Kv7.5 , voltage-gated potassium channel type Kv7.5

GENE ID SPECIES
462817 Pan troglodytes
556841 Danio rerio
613605 Bos taurus
100411503 Callithrix jacchus
259273 Rattus norvegicus
56479 Homo sapiens
474965 Canis lupus familiaris
100328657 Oryctolagus cuniculus
226922 Mus musculus
100154391 Sus scrofa
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