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The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development.
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Human Monoclonal PSG1 Primary Antibody for IHC (f), IHC (fro) - ABIN2689377
Engvall, Miyashita, Ruosiahti: Monoclonal antibodies in analysis of oncoplacental protein SP1 in vivo and in vitro. in Cancer research 1982
Inhibiting PSG1 can effectively reduce chemoresistance via a transforming growth factor-beta (TGF-beta)-related pathway in ER-negative breast cancer cells.
PSG stimulated IDO (show IDO1 Antibodies) activity under the conditions of induction of the monocytes by interferon-gamma (show IFNG Antibodies).
Under conditions of directed induction of phenotypic changes in CD4 (show CD4 Antibodies)(+) lymphocytes to regulatory T cells (Treg), pregnancy-specific at high concentrations (10 and 100 mug/mL) increased FOXP3 (show FOXP3 Antibodies) expression. The evaluation of the spontaneous expression level of FOXP3 (show FOXP3 Antibodies) mRNA showed that pregnancy-specific beta1-glycoprotein (1 and 100 mug/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4 (show CD4 Antibodies)(+) lym...
results identify a non-placental site of PSG expression in the gut (show GUSB Antibodies) and associated tumors, with implications for determining whether PSGs have a role in tumor progression, and utility as tumor biomarkers.
the presence of GAGs on the surface of endothelial cells was required for the ability of PSG1 to induce tube formation
The aspartic acid at position 95 is not required for PSG1 activity but the amino acids implicated in the formation of a salt bridge within the N-domain are essential.
The differential expression of HLA-E (show HLAE Antibodies) and PSG1 in the sperm of fertile and infertile men is discussed.
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976
CD66 antigen-like family member F
, fetal liver non-specific cross-reactive antigen 1/2
, pregnancy-specific B-1 glycoprotein
, pregnancy-specific beta-1 glycoprotein C/D
, pregnancy-specific beta-1-glycoprotein 1
, pregnancy-specific glycoprotein 1
, pregnancy specific beta-1-glycoprotein 1
, pregnancy specific beta-1-glycoprotein 1 pseudogene
, pregnancy specific beta-1-glycoprotein 12
, pregnancy specific beta-1-glycoprotein 120
, pregnancy-specific beta-1 glycoprotein