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The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. Additionally we are shipping PSG9 Proteins (4) and PSG9 Kits (1) and many more products for this protein.
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Results indicate that pregnancy-specific glycoprotein 9 (PSG9) may facilitate the development of hepatocellular carcinoma (HCC (show FAM126A Antibodies)) by fostering angiogenesis via promoting VEGFA (show VEGFA Antibodies) production in cancer HCC (show FAM126A Antibodies).
Findings illustrate the innovative mechanism by which PSG9 drives the progression of colorectal cancer and tumor angiogenesis. This occurs via nuclear translocation of PSG9/SMAD4 (show SMAD4 Antibodies), which activates angiogenic cytokines.
PSG9, through its activation of TGFbeta (show TGFB1 Antibodies)-1, could be a potent inducer of immune tolerance
PSG9 may have a role in development of colorectal carcinogenesis in patients with adenomatous polyposis coli (show APC Antibodies)
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).
pregnancy-specific beta-1-glycoprotein 9
, pregnancy-specific beta-1 glycoprotein B
, pregnancy specific beta-1-glycoprotein 11