anti-Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) Antibodies

The protein encoded by PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. Additionally we are shipping Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Kits (57) and Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Proteins (55) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPBP 57349  
PPBP 5473 P02775
PPBP 246358  
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Top anti-Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Antibodies at antibodies-online.com

Showing 10 out of 131 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PPBP antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-PPBP Pab in CEM cell line lysates (35ug/lane). PPBP(arrow) was detected using the purified Pab (1:60 dilution). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PPBP (arrow) using rabbit polyclonal PPBP Antibody 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: NAP2 Antibody [NBP1-89921] - Staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes of bone marrow poietic cells. Western Blot: NAP2 Antibody [NBP1-89921] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB Western blot analysis of PPBP (arrow) using rabbit polyclonal PPBP Antibody (N-term) (ABIN391800). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PPBP gene (Lane 2) (Origene Technologies).(8 µg/mL) Anti-PPBP Antibody (N-term) at 1:1000 dilution + human spleen lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 14 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:1000 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-PPBP Pab (ABIN391801) in CEM cell line lysates (35 µg/lane). PPBP(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PPBP antibody (C-term) (ABIN391801), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Western blot analysis of NAP2 expression in MCF-7 whole cell lysates (lane 1). NAP2 at 19KD was detected using rabbit anti- NAP2 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method NAP2 was detected in paraffin-embedded sections of human placenta tissues using rabbit anti- NAP2 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of extracts of mouse liver, using PPBP antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276958 at 1/100 staining Human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Anti-PPBP antibody IHC staining of human intravascular platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103722 concentration 5 ug/ml. Anti-PPBP antibody IHC of human intravascular platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), Neut, WB Anti-PPBP antibody IHC staining of human intravascular platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103721 concentration 5 ug/ml. Anti-PPBP antibody IHC of human intravascular platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded human liver cancer using PPBP antibody at dilution of 1:100 (40x lens). 100 μL Log in to see 16 Days
$366.77
Details

Top referenced anti-Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Antibodies

  1. Human Polyclonal PPBP Primary Antibody for ELISA, WB - ABIN543917 : Majumdar, Gonder, Koutsis, Poncz: Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4. in The Journal of biological chemistry 1991 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PPBP Primary Antibody for IHC, IHC (p) - ABIN4301104 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

More Antibodies against Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Interaction Partners

Mouse (Murine) Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) interaction partners

  1. Low CXCL7 expression is associated with posterior longitudinal ligament ossification.

  2. CXCR4(+) CD45(-) bone marrow cells are niche forming for osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 signaling pathways in bone marrow.

  3. This is the first report that demonstrates Ppbp as a novel biomarker in the bronchial airway for lung cancer diagnosis.

  4. Platelet-derived CXCL7 and CXCL4 contribute to the pathogenesis of acute lung injury.

  5. The findings suggest that CXCL7 attracts macrophages especially at the tumor site and may accelerate lung tumor development in the early stages.

  6. These results suggest that Cxcl4 and Cxcl7 play a role in the development of neurobehavioral alterations that are triggered by in utero TCDD exposure and later surface in adults.

Human Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) interaction partners

  1. Low CXCL7 expression is associated with posterior longitudinal ligament ossification.

  2. In the prospective population-based Atherosclerosis Risk in Communities cohort, beta-thromboglobulin was not associated with cardiovascular disease risk.

  3. Cleavage of a factor Xa-specific chromogenic substrate was observed when Beta-TG was incubated with factor X, suggesting a direct interaction between Beta-TG and factor X. Beta-TG modulate coagulation in vitro via an interaction with factor X.

  4. This study demonstrated that platelet basic protein was detected in the serums of Alzheimer disease patients

  5. DEFA1, DEFA3, and PPBP expression was significantly increased in hyperlipidemia and coronary heart disease patients compared with controls.

  6. These results suggest that aberrant CXCL7 expression in peripheral blood cells is induced by renal cell carcinoma cells and may serve as a novel biomarker in the diagnosis of renal cell carcinoma .

  7. Two haplotype blocks, one upstream to the coding region of UGT2A1 (rs146712414, P = 9.1 x 10(-5); odds ratio [OR], 1.34; 95% confidence interval [CI], 1.16-1.56) and one downstream of the genes PF4/PPBP/CXCL5 (rs1595009, P = 1.3 x 10(-4); OR, 1.32; 95% CI, 1.15-1.52), were associated with AgP.

  8. NMR and modeling studies indicated that glycosaminoglycans (GAG) heparin binding to the heterodimer is distinctly different from the CXC chemokine ligand 7 (CXCL7) monomer.

  9. Cby's C-terminal domain alone binds to TC-1 with significantly greater affinity compared to full-length Cby, implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  10. CXCL7 plays a promoting role in regulating the growth and metastasis of cholangiocarcinoma.

  11. Data suggest that neutrophil-activating peptide 2 (NAP-2) secreted by NK cells can bind to CXC Chemokine Receptor 2 (CXCR2) on mesenchymal stem cells (MSCs) leading to stimulation of its recruitment.

  12. Utilizing mass spectrometry-based proteomics, platelet basic protein has been identified as a candidate serum biomarker for transient ischemic attack

  13. Synovial Cxcl7 mRNA and protein were increased in early rheumatoid arthritis compared to uninflamed controls and resolving arthritis.

  14. Studied and characterized the dynamics and thermodynamic stability of monomer and homodimer structures of CXCL7.

  15. Leptin and neutrophil-activating peptide act synergistically to promote mesenchymal stem cell senescence through enhancement of the PI3K/Akt signaling pathway in systemic lupus erythematosus patients.

  16. CXCL7/CXCR2 signalling pathways are a predictive factor of poor outcome in metastatic colon cancer.

  17. CXCR4-CXCL12-CXCR7 regulates mTOR signaling in renal cancer cells.

  18. The antimicrobial thrombocidin peptides are found in human blood platelets, are deletion products of CXC chemokines and have antibacterial and antifungal activity.

  19. The level of beta-thromboglobulin was found significantly higher in female patients with rheumatoid arthritis.

  20. Testing of bacterial resistance to platelet antimicrobial lmw proteins (PMPs) may be advisable as a predictive indicator of susceptibility to treatment of infections such as infective endocarditis and other local infections of biofilm nature.

Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) Antigen Profile

Protein Summary

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Gene names and symbols associated with PPBP

  • Platelet basic protein (scyb7) antibody
  • pro-platelet basic protein (Ppbp) antibody
  • pro-platelet basic protein (PPBP) antibody
  • 2400003M24Rik antibody
  • AI854500 antibody
  • B-TG1 antibody
  • Beta-TG antibody
  • CTAP-III antibody
  • CTAP3 antibody
  • CTAPIII antibody
  • CTAPIII/NAP-2 antibody
  • CXCL7 antibody
  • LA-PF4 antibody
  • LDGF antibody
  • MDGF antibody
  • Nap-2 antibody
  • NAP-2-L1 antibody
  • PBP antibody
  • SCYB7 antibody
  • TC1 antibody
  • TC2 antibody
  • TGB antibody
  • TGB1 antibody
  • THBGB antibody
  • THBGB1 antibody

Protein level used designations for PPBP

Platelet basic protein , chemokine (C-X-C motif) ligand 7 , platelet basic protein , C-X-C motif chemokine 7 , CXC chemokine ligand 7 , beta-thromboglobulin , connective tissue-activating peptide III , leukocyte-derived growth factor , low-affinity platelet factor IV , macrophage-derived growth factor , neutrophil-activating peptide 2 , neutrophil-activating peptide-2 , small inducible cytokine B7 , small inducible cytokine subfamily B, member 7 , small-inducible cytokine B7 , thrombocidin 1 , thrombocidin 2 , thromboglobulin, beta-1 , neutrophil activating peptide-2 , PBP

GENE ID SPECIES
100196194 Salmo salar
57349 Mus musculus
5473 Homo sapiens
246358 Rattus norvegicus
396870 Sus scrofa
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