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a proline rich protein found enriched in bronchiolar epithelial cells [RGD, Feb 2006].. Additionally we are shipping and and many more products for this protein.
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PNRC1 ablates the enhanced proliferation triggered by established oncogenes such as RAS and MYC These observations uncover a previously undescribed mechanism of tumor suppression, whereby the cytoplasmic decapping machinery is hauled within nucleoli, tightly regulating ribosomal RNA maturation.
PNRC and Grb2, by interacting with each other, can suppress nuclear receptor-mediated regulation and growth factor-mediated regulation in human breast tissue
Functional analysis of the 5' flanking region of the human PNRC gene by deletion mutagenesis, transient transfection and luciferase assays revealed that the -123/+27 region is the minimal promoter of the human PNRC gene.
Three human PNRC splicing variants designated PNRC1c, PNRC1d and PNRC1f, are identified.
RFX1 specifically bind to promoter region and negatively regulate the transcription of the human PNRC gene.
a proline rich protein found enriched in bronchiolar epithelial cells
proline rich 2 protein
, proline-rich polypeptide 2
, proline-rich protein 2
, proline-rich protein with nuclear targeting signal
, protein B4-2
, proline rich 2
, proline-rich nuclear receptor coactivator 1